Research Keyword: agricultural fungicide

Microminutinin, a Fused Bis-Furan Coumarin from Murraya euchrestifolia, Exhibits Strong Broad-Spectrum Antifungal Activity by Disrupting Cell Membranes and Walls

mycolabadmin

Researchers discovered a natural compound called microminutinin from a plant used in traditional medicine. This compound shows strong ability to kill various fungal pathogens that damage crops, particularly tea plants. The compound works by breaking down the protective structures of fungal cells, making it a promising candidate for developing safer, plant-based fungicides for agriculture.

Read More »

Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani

mycolabadmin

Scientists tested a plant-based extract from Cinchona bark as a natural fungicide against a serious fungus that damages rice crops. The active ingredient, quinine, works by two methods: it blocks the fungus from getting the amino acid tryptophan it needs to survive, and it damages the fungus’s energy-producing structures. When researchers added tryptophan back to the treated fungus, it recovered, confirming this is how the treatment works. This natural fungicide could offer farmers an eco-friendly alternative to chemical pesticides.

Read More »

Comprehensive analysis of the mechanisms conferring resistance to phenamacril in the Fusarium species

mycolabadmin

Fusarium fungi cause serious diseases in crops like wheat, corn, and fruits, causing huge losses in agriculture worldwide. Phenamacril is a new antifungal drug designed specifically to fight these fungi by blocking a protein they need to grow. However, the fungi are developing resistance to this drug through genetic mutations and other biological mechanisms, making it less effective over time. Understanding how this resistance develops helps scientists develop better strategies to maintain the drug’s effectiveness and protect our food supply.

Read More »
Scroll to Top