adaptive immunity – mycolab.ai

Tumor-associated macrophages in tumor progression and the role of traditional Chinese medicine in regulating TAMs to enhance antitumor effects

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This review explains how tumor-associated macrophages (immune cells) can either fight or help cancer depending on their type. Traditional Chinese Medicine contains compounds that can reprogram these macrophages to fight cancer more effectively. By shifting macrophages from a cancer-supporting state to a cancer-fighting state, TCM treatments could enhance the body’s natural ability to combat tumors and reduce side effects of conventional cancer therapies.

Bibliometric analysis of traditional Chinese medicine for viral infections through immune modulation (2015–2025)

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This research analyzed over 3,300 scientific papers published between 2015-2025 to understand how traditional Chinese medicine helps fight viral infections by boosting the immune system. The study found that research on this topic has grown significantly, especially during disease outbreaks like COVID-19, with China leading in research publications. Key findings show that traditional Chinese herbal compounds work through multiple mechanisms including directly fighting viruses, reducing excessive inflammation, and enhancing vaccine effectiveness. The research points toward promising future applications of traditional Chinese medicine when combined with modern medical approaches.

Evaluation of Immune Modulation by β-1,3; 1,6 D-Glucan Derived from Ganoderma lucidum in Healthy Adult Volunteers, A Randomized Controlled Trial

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A study tested whether a supplement made from Reishi mushroom could boost immune system function in healthy adults. Over 84 days, people taking the Reishi β-glucan supplement showed significant improvements in immune cells and antibodies compared to those taking a placebo. The supplement was safe and well-tolerated with no negative side effects, suggesting it may help strengthen the body’s natural defenses against infections.

Immune regulatory functions of biologically active proteins from edible fungi

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This research compared how proteins from 22 different edible mushrooms affect immune system cells called macrophages. The study found that all the mushroom proteins tested boosted immune function by making macrophages more active and productive. Interestingly, expensive rare mushrooms like cordyceps and ganoderma lucidum had stronger immune-boosting effects than common grocery store mushrooms like oyster and button mushrooms.

The dimorphic fungus Talaromyces marneffei: An opportunistic killer in Southeast Asia

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Talaromyces marneffei is a dangerous fungus found in Southeast Asian soils that causes serious lung infections when people breathe in its spores. The fungus has a clever trick: it transforms into different forms depending on temperature and hides inside immune cells by tricking them. People with weak immune systems, particularly those with advanced HIV/AIDS or certain genetic conditions, are most vulnerable to severe disease.

Dectin-1 and dectin-2 drive protection against Sporothrix brasiliensis in experimental sporotrichosis

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Scientists studied how the immune system fights a dangerous fungal infection called sporotrichosis caused by Sporothrix brasiliensis. They found that two immune receptors called dectin-1 and dectin-2 are crucial for fighting this infection by activating specific killer T cells and preventing immune suppression. Unlike what was previously thought, these receptors don’t work mainly by triggering inflammation, but rather by fine-tuning the balance of different immune cell types. This discovery could help develop new treatments for this emerging fungal disease.

Natural Ingredients to Improve Immunity

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Many natural ingredients from plants, mushrooms, and other sources can boost your immune system and help fight infections. These include well-known items like garlic, ginger, and vitamin C, as well as lesser-known compounds like β-glucans from mushrooms and melatonin from plant sources. Proper nutrition with adequate vitamins and minerals is crucial for maintaining a strong immune system that protects you from disease without overreacting and causing autoimmune problems.

Immunomodulatory function of chitosan is dependent on complement receptor 3

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This study reveals how the human immune system recognizes chitosan, a natural component found in the walls of disease-causing fungi like Aspergillus and Cryptococcus. Researchers discovered that immune cells use a protein called CR3 on their surface to detect and respond to chitosan by producing inflammatory chemicals that help fight infection. When chitosan works together with fungal proteins, it can boost the immune system’s response even more effectively, suggesting new ways to enhance immunity against fungal infections.

Aspergillus in Children and Young People with Cystic Fibrosis: A Narrative Review

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Cystic fibrosis is a serious genetic disease affecting children that damages the lungs through chronic infections. Aspergillus, a common mold in the environment, colonizes the airways of CF patients and can cause additional lung damage. While new CFTR modulator medications have improved outcomes and reduced Aspergillus infections, more research is needed to better diagnose and treat fungal infections in children with CF.

Potential relationship between gut microbiota and animal diarrhea: a systematic review

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This review explains how the trillions of microorganisms living in animal intestines are crucial for health and digestion. When these microbial communities become imbalanced, animals develop diarrhea, which is a major problem in farming causing economic losses and animal suffering. The review shows that adding beneficial bacteria (probiotics) and their food sources (prebiotics) to animal diets can restore balance and prevent diarrhea, offering practical solutions to reduce the need for antibiotics.

Research Keyword: adaptive immunity