Research Keyword: acute kidney injury

A Terrible Trip: Tubulointerstitial Nephritis and Uveitis Syndrome Triggered by Psilocybe Mushroom Ingestion

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A patient experienced serious kidney and eye inflammation after ingesting psilocybe mushrooms, which are known for their hallucinogenic properties. This rare combination of symptoms, called TINU syndrome, had not been previously associated with mushroom use. The case highlights an unexpected and serious health risk from consuming hallucinogenic mushrooms, suggesting that the active compounds may trigger severe inflammatory responses in some individuals.

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Acute Kidney Failure and Myocarditis Triggered by Magic Mushroom Toxicity in a Patient With Prior Cocaine Exposure

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A middle-aged man who used magic mushrooms along with alcohol and LSD developed severe kidney failure and heart inflammation. He had previously used cocaine, which made his condition worse by promoting blood clots throughout his body. Despite dialysis treatment, his kidneys stopped working, he developed heart problems and blood clots in major blood vessels, and he unfortunately passed away. This case highlights how dangerous it can be to mix magic mushrooms with other drugs, especially for people with a history of cocaine use.

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Increased Rates of Supplement-Associated Oxalate Nephropathy During COVID-19 Pandemic

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During the COVID-19 pandemic, more people took dietary supplements and high-dose vitamin C for health reasons. However, this study found that excessive supplement intake led to a significant increase in a kidney disease called oxalate nephropathy, where calcium oxalate crystals damage the kidneys. The good news is that when patients stopped taking these harmful supplements, their kidney function often improved, emphasizing the importance of careful supplement use.

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Local mushroom poisoning: a case report study

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A 26-year-old woman became severely ill after eating poisonous mountain mushrooms she mistakenly thought were edible. She developed serious heart problems, elevated liver enzymes, and inflammation of the pancreas, requiring intensive care and a heart defibrillator shock. After receiving NAC (N-acetylcysteine) infusions and dialysis for a week, she gradually recovered and was eventually discharged in good condition. This case highlights the dangers of wild mushroom foraging and the importance of seeking immediate medical attention if poisoning is suspected.

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Natural Products in Renal-Associated Drug Discovery

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This research examines how natural products like green tea and medicinal mushrooms can help treat kidney diseases. Scientists reviewed various plants used in traditional medicine and analyzed how compounds from these plants affect gene expression in kidney cells. The study identified specific genes and biological pathways that explain how these natural antioxidants and anti-inflammatory agents protect kidneys from injury and disease.

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