Research Keyword: ABC transporter

A putative ABC transporter gene, CcT1, is involved in beauvericin synthesis, conidiation, and oxidative stress resistance in Cordyceps chanhua

Cordyceps chanhua is a medicinal fungus used in traditional Chinese medicine that produces a compound called beauvericin, which has health benefits but can be toxic in high amounts. Researchers discovered a gene called CcT1 that controls how much beauvericin the fungus makes. By removing this gene, they could reduce beauvericin production by 64%, making the fungus safer to use as medicine while maintaining other beneficial properties.

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The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection

This research reveals how corn fungi protect themselves from their own toxic products by employing specialized defense enzymes. Scientists discovered that five genes work together in a protective cluster, with some enzymes strengthening the fungal cell’s natural defenses while others actively break down the toxin. This discovery helps explain how dangerous fungi survive and could lead to better strategies for preventing mycotoxin contamination in crops and developing disease-resistant plants.

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