Research Keyword: β-glucans

Glycan microarray analysis of Candida-related antibodies in human and mice sera guides biomarker discovery and vaccine development

Researchers developed a test using synthetic sugar molecules found on Candida yeast to detect antibodies in blood from infected patients and mice. They discovered that the immune system produces different antibodies at different stages of infection, starting with antibodies against certain sugars and later focusing on others. The study identified three specific sugar structures that could be used to create simple blood tests to diagnose Candida infections and potentially develop vaccines to prevent these serious fungal infections.

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Effects of a biotechnologically produced Pleurotus sapidus mycelium on gut microbiome, liver transcriptome and plasma metabolome of broilers

Researchers tested whether mushroom mycelium grown using agricultural waste could be safely added to chicken feed. The mycelium, rich in beneficial compounds like β-glucans, was added to broiler diets at varying levels for 35 days. Results showed that chickens fed diets containing up to 5% mushroom mycelium performed just as well as control chickens, with no negative effects on health, digestion, or metabolism, suggesting this sustainable feed ingredient could help reduce competition between animal feed and human food.

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A concise review of mushrooms antiviral and immunomodulatory properties that may combat against COVID-19

This review explores how medicinal mushrooms have compounds that could help fight COVID-19 and boost immune function. Various mushroom species contain natural substances like beta-glucans and polysaccharides that have shown antiviral properties and can strengthen the body’s immune response. The research suggests these mushrooms could potentially be used alongside conventional treatments to help patients recover from COVID-19 more effectively.

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Influence of Pleurotus sapidus fruiting bodies on the performance, cecal microbiome, and gene expression in the liver and breast muscle of broilers

Researchers tested whether edible mushroom fruiting bodies could be used as animal feed for chickens. They found that chickens fed diets containing oyster mushroom (Pleurotus sapidus) had reduced growth and lower nutrient absorption compared to control chickens. While mushroom-based feed appeared to increase beneficial gut bacteria diversity, it ultimately impaired overall chicken performance, suggesting mushroom fruiting bodies are not suitable as a primary feed component for commercial poultry production.

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