Type 2 Diabetes Mellitus – Page 2

A Systematic Review on Important Risk Factors and Possible Involved Mechanisms of Medicinal Plants on Nonalcoholic Fatty Liver Disease

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This comprehensive review examined 43 medicinal plants that can help prevent and treat fatty liver disease (NAFLD), which is increasingly common in developed countries. Most of these plants work by reducing cholesterol and triglycerides, helping with weight management, improving blood sugar control, and lowering blood pressure. The plants contain natural compounds like flavonoids and polyphenols that reduce inflammation and oxidative stress in the liver. Using these herbal supplements alongside other lifestyle changes may offer a promising natural approach to managing NAFLD and its related conditions.

Pulmonary Mucormycosis in Diabetic Patients: A Case Series From a Tertiary Respiratory Center in Sri Lanka

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This case study describes three diabetic patients in Sri Lanka who developed a serious lung infection caused by a fungus called mucormycosis. The infection caused cavities in the lungs and symptoms like fever, cough, and weight loss. Two patients recovered with antifungal medication (amphotericin B) and surgery, while one patient sadly died despite receiving treatment. The study emphasizes that doctors should consider this infection in diabetic patients with unusual lung symptoms to catch it early.

Fortifying a meal with oyster mushroom powder beneficially affects postprandial glucagon-like peptide-1, non-esterified free fatty acids and hunger sensation in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial

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This study tested whether adding powdered oyster mushrooms to a meal could help people with impaired glucose tolerance manage their blood sugar and appetite. While the mushroom powder didn’t reduce blood glucose spikes as expected, it did lower fat levels in the blood, increase a hormone that promotes fullness, and reduced hunger. The results suggest that adding oyster mushroom powder to meals could be a simple dietary change that helps prevent diabetes and weight gain.

New bioactive secondary metabolites from fungi: 2024

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Scientists discovered 907 new compounds from fungi in 2024, with most being terpenoids and polyketides that show promise as medicines. These fungal compounds demonstrate strong activity against bacteria, fungi, and inflammation, with some showing potential against cancer and diabetes. The research uses advanced techniques like genome mining and metabolomics to find these compounds more efficiently. This accelerating discovery rate suggests fungi could be a major source for developing new drugs to treat various diseases.

Synergistic target network construction and dynamic simulation analysis based on a prospective systems pharmacology strategy

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Researchers used computer-based methods to study how Sang Huang, a traditional medicinal fungus, might help treat type 2 diabetes. They identified 17 active compounds in the fungus and found that a key component called estradiol dipropionate could improve insulin sensitivity and glucose control by activating specific protein pathways. The study suggests Sang Huang could be a promising natural treatment for diabetes, though more laboratory and animal testing is needed.

Pulmonary Mucormycosis in Diabetic Patients: A Case Series From a Tertiary Respiratory Center in Sri Lanka

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This case study describes three patients with diabetes who developed a serious lung infection caused by a rare fungus called mucormycosis. The infection presented with various symptoms like cough, fever, and weight loss, and was diagnosed using lung tissue samples that showed the characteristic fungal structures. Two patients recovered with prolonged antifungal medication treatment, while one patient unfortunately died despite receiving prompt treatment, highlighting how serious this infection can be.

Innovative applications and therapeutic potential of oilseeds and their by-products: An eco-friendly and sustainable approach

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This review explains how leftover materials from oilseed processing, which are usually discarded as waste, contain valuable nutrients and healing compounds. These by-products can be used to make healthier foods like bread, burgers, and drinks, or turned into supplements and medicines. By using these materials instead of wasting them, we can reduce environmental problems, provide better nutrition, and create sustainable food products that help prevent diseases like diabetes and heart problems.

Case Report: Liquid-based cytology diagnosis of pulmonary mucormycosis

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A 41-year-old man with diabetes developed a serious lung infection caused by mucormycosis, a rare and dangerous fungus. Doctors diagnosed the infection using liquid-based cytology, a technique that examines fluid from the lungs under a microscope, which proved more effective than traditional methods. Treatment with antifungal medications helped stabilize the patient’s condition, and he remained healthy during an eight-month follow-up. This case highlights how advanced diagnostic techniques can help doctors quickly identify and treat severe fungal infections.

Novel Approaches in Glucose and Lipid Metabolism Disorder Therapy: Targeting the Gut Microbiota–Bile Acid Axis

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Your gut bacteria play a key role in how your body manages blood sugar and fats, working through molecules called bile acids. Researchers have discovered that certain foods, supplements, and herbs can improve this gut bacteria-bile acid interaction to help prevent or treat diabetes and obesity. This review explains how these natural interventions work and suggests promising new ways to treat metabolic diseases by harnessing your gut health.

Schizophyllum commune infection following chimeric antigen receptor T-cell therapy in a patient with lymphoma

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A 71-year-old woman receiving CAR T-cell therapy for lymphoma developed a rare fungal lung infection caused by Schizophyllum commune six months after treatment. The infection presented similarly to other fungal diseases affecting the lungs and was diagnosed through bronchoscopy and fungal culture despite negative blood antibody tests. Standard antifungal medication (voriconazole) taken by mouth for four months completely resolved the infection, highlighting the need to consider rare fungi in patients receiving advanced cancer immunotherapies.

Disease: Type 2 Diabetes Mellitus