Disease: tumors

Soil Fungal Diversity and Community Structure of Russula griseocarnosa from Different Sites

Researchers studied the soil fungi living around Russula griseocarnosa, a valuable wild edible mushroom that cannot be grown in farms. They found that the soil around this mushroom contains specific beneficial fungi like Penicillium and Trichoderma that help it grow, and that these fungal communities differ depending on geographical location. The study shows that using fertilizers containing nitrogen, phosphorus, potassium, and beneficial fungi could help protect and increase the production of this wild mushroom.

Read More »

Telomere-to-Telomere Assembly of the Cordyceps militaris CH1 Genome and Integrated Transcriptomic and Metabolomic Analyses Provide New Insights into Cordycepin Biosynthesis Under Light Stress

Researchers successfully sequenced the complete genome of Cordyceps militaris CH1, a medicinal fungus used in traditional Chinese medicine. By exposing the fungus to light and analyzing gene expression and metabolite changes, they discovered that light stress activates key genes involved in producing cordycepin, the main active medicinal compound. This breakthrough provides a foundation for improving cordycepin production in artificial cultivation, making this valuable medicine more affordable and accessible.

Read More »

Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

Researchers studied how special fungal compounds called elicitors can boost the production of healing substances in a medicinal mushroom called Sanghuangporus sanghuang. By analyzing genes and metabolites, they found that adding elicitors increased beneficial compounds like betulinic acid and 2-hydroxyoleanolic acid by up to 114-fold. These findings suggest a practical way to produce more medicinal compounds from this mushroom for health applications.

Read More »

Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

Scientists studied how a special fungal treatment can boost the production of beneficial compounds in sanghuang mushrooms. Using advanced molecular analysis techniques, they found that the fungal elicitor significantly increased levels of healing compounds called triterpenes. The treated mushrooms produced 114 times more of one specific compound compared to untreated mushrooms. This research shows how we can grow medicinal mushrooms with higher levels of beneficial substances, which could help develop better treatments for various diseases.

Read More »

Continuous motion of particles attached to cavitation bubbles

Researchers discovered that cavitation bubbles (tiny bubbles created by ultrasound) can push particles through liquid in a controlled manner. The bubbles expand and collapse in a way that creates a net forward push, similar to a pulse engine. This discovery could revolutionize drug delivery by allowing medications to be attached to particles and guided through the body using ultrasound, potentially improving treatments for heart disease and cancer.

Read More »

Whole genome sequencing and annotations of Trametes sanguinea ZHSJ

Scientists sequenced the complete genome of Trametes sanguinea, a medicinal mushroom used in traditional Chinese medicine, grown in China. The mushroom’s tissue contains beneficial compounds that may help fight tumors, protect the heart, boost immunity, and heal diabetic wounds. By mapping out all 10,886 genes in this fungus, researchers now have detailed blueprints to understand how it produces these healing compounds and potentially grow them industrially for medical use.

Read More »

Composition and Biodiversity of Culturable Endophytic Fungi in the Roots of Alpine Medicinal Plants in Xinjiang, China

Scientists studied special fungi that live inside the roots of two rare alpine medicinal plants found in China’s high mountains. They discovered that these plants host over 400 different types of fungi, including a special type called dark septate fungi that make up about half of all the fungi found. Different plant species and different mountain locations had different combinations of fungi, suggesting these fungi help the plants survive in the harsh, cold mountain environment.

Read More »

Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

Researchers compared two types of medicinal fungi (Phylloporia crataegi and Phylloporia fontanesiae) to understand why one is better at fighting cancer. They used advanced techniques to examine the fungi’s chemicals, genes, and proteins, discovering that P. crataegi contains special compounds like trans-cinnamic acid that help kill cancer cells. This study provides important information for developing new cancer treatments from these fungi.

Read More »

Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

Two species of medicinal fungi were studied to understand why one was better at fighting cancer cells. Researchers analyzed the chemicals, genes, and proteins in both fungi and found that Phylloporia crataegi had much higher levels of cancer-fighting compounds and activated special cellular defense pathways that harm cancer cells. This research shows that medicinal fungi could be promising sources for developing new cancer treatments.

Read More »
Scroll to Top