Disease: tuberculosis

Access to diagnostic testing for invasive fungal diseases and other opportunistic infections in Mexican health care centers caring for patients living with HIV

This study examined the availability of diagnostic tests for fungal and other serious infections in Mexican HIV clinics. Researchers found that most clinics, especially smaller primary care facilities, lack modern rapid testing equipment needed to quickly diagnose dangerous infections like cryptococcosis and histoplasmosis. These infections are common in people with advanced HIV and can be life-threatening, making access to rapid diagnosis crucial for treatment and survival.

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mGem: Sepsis and antimicrobial resistance in the context of advanced HIV disease

This review examines how serious infections (sepsis) from bacteria and fungi affect people with advanced HIV disease, particularly in hospitals. The infections have become more dangerous due to antimicrobial resistance, and many cases go undiagnosed because of limited laboratory capabilities. The paper calls for better diagnostic tools and treatment strategies tailored to resource-limited settings where most advanced HIV disease cases occur.

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Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action

Ganoderma is a medicinal mushroom that has been used in traditional medicine for thousands of years and is now being studied for its ability to fight infections. The mushroom contains special compounds like polysaccharides and triterpenoids that can kill harmful bacteria and fungi in multiple ways—by breaking down their cell walls, stopping them from reproducing, and boosting your immune system. Scientists have found that Ganoderma works against many dangerous bacteria including antibiotic-resistant strains, and it may offer a natural alternative to conventional antibiotics as antibiotic resistance becomes a major global health problem.

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Survey of clinical microbiology and infectious disease testing capabilities among institutions in Africa

This study surveyed laboratory facilities across Africa to understand what infectious disease tests are available. Researchers found that basic tests like bacterial identification are common, but advanced tests for viruses (other than HIV) and fungi are less available. The study highlights the need for investment in laboratory infrastructure to improve disease diagnosis and help countries respond to health emergencies.

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Clinical characterization of immunocompetent patients with Scedosporium detected in respiratory samples: A case series

This study examined eight elderly patients without compromised immune systems who had the fungus Scedosporium detected in their lungs. All patients had a condition called bronchiectasis, and most had previously suffered from MAC disease. The researchers found that in most cases, the fungus was just colonizing the lungs without causing active infection. The challenge for doctors is determining whether Scedosporium is simply living in the lungs or actively causing disease.

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Awareness and perception of invasive fungal diseases among the Nigerian population

This study found that very few Nigerians (only about 19%) are aware of serious fungal infections like candidiasis and aspergillosis, and most people don’t understand how dangerous these diseases can be. The researchers surveyed over 1,200 people and discovered that people with more education and higher incomes were more likely to know about these infections. The findings suggest that Nigeria urgently needs public health campaigns and education programs to help people recognize fungal diseases early so they can get proper treatment.

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What’s in a name? Fit-for-purpose bacterial nomenclature: meeting report

Scientists are discovering and renaming bacteria so rapidly that doctors and other professionals sometimes don’t recognize the new names, which can cause confusion in patient care and food safety. This meeting brought together experts to discuss the problem and create better systems for managing these changes. The key finding is that when bacteria get new scientific names, there needs to be better communication with the practical users like clinicians so they stay informed and can provide proper treatment.

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Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action

Ganoderma is a medicinal mushroom that has been used in traditional medicine for thousands of years and shows promise as a natural antibiotic. The mushroom contains special compounds like polysaccharides and triterpenoids that can kill harmful bacteria and fungi by damaging their cell walls and boosting your immune system. Recent research shows it works against common infections like those caused by staph bacteria and E. coli, and may even help fight antibiotic-resistant germs.

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Disseminated subcutaneous sporotrichosis in an immunocompetent patient: A case report and a systematic literature review

A 74-year-old man developed painful red masses on his arm and hand after being stuck by a tree branch. Tests identified the infection was caused by a fungus called Sporothrix schenckii. Despite having a normal immune system, the infection had spread across his arm in an unusual pattern. Treatment with an antifungal medication called itraconazole completely healed the lesions within four months without any scarring.

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