Disease: tinea corporis

Identification of Challenging Dermatophyte Species Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

This study shows that MALDI-TOF mass spectrometry is an effective method for quickly identifying skin fungal infections caused by dermatophytes. By combining commercial reference databases with a custom library created from local isolates, researchers achieved 90.7% accurate identification compared to only 16.1% using the commercial database alone. This improved method could help doctors diagnose and treat fungal skin infections more quickly and accurately in clinical laboratories.

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Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

Researchers in Thailand have identified the first cases of a new resistant fungal skin infection caused by Trichophyton indotineae. This fungus is resistant to a commonly used antifungal drug called terbinafine and causes persistent skin rashes on various body parts. The study describes five patients whose infections were finally identified through genetic testing and who responded well to alternative antifungal treatment with itraconazole. This discovery suggests the fungus is now spreading in Thailand and doctors should watch for it.

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Randomized control trial to study the effectiveness of tablet Fluconazole, capsule Itraconazole and tablet Terbinafine in superficial dermatophytosis

This study tested three common antifungal medications used to treat fungal skin infections like ringworm. The research involved 180 patients who were randomly given one of three drugs and then checked at 4 and 8 weeks to see if the infection was gone. Itraconazole worked best, clearing infections in about 87% of patients, followed by Fluconazole at 73%, and Terbinafine at 63%.

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Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

Doctors in Thailand have identified a new drug-resistant fungal infection caused by Trichophyton indotineae, a fungus that doesn’t respond to common antifungal medication terbinafine. Five patients were diagnosed with this resistant skin infection that caused rashes on various body parts and failed to improve with standard treatments. The research shows that a simple urease test can help doctors quickly identify this resistant fungus, and a different drug called itraconazole appears to work better for treatment. This is the first time this resistant fungus has been confirmed in Thailand, suggesting it is spreading globally.

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Unmasking Tinea Incognito: Case Study, Insights Into the Pathogenesis, and Recommendations

A 29-year-old woman was incorrectly treated for psoriasis with steroids, which made her fungal infection worse instead of better. When doctors finally diagnosed her with a fungal infection (tinea incognito), they found it was caused by a common dermatophyte fungus. This case highlights how steroid creams can hide fungal infections and make them spread, and shows why recognizing this condition is important for proper treatment.

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Identification of Challenging Dermatophyte Species Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

This study shows that a specialized technique called MALDI-TOF mass spectrometry can accurately identify fungal skin infections by analyzing protein patterns. Researchers created a customized library of local fungal species that, when combined with commercial databases, improved identification accuracy from 16% to 91%. This advancement helps doctors quickly identify the exact type of fungal infection patients have, enabling faster and more appropriate treatment decisions.

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Northwest Iranian dermatophyte isolates: anthropophilic and geophilic

Researchers in northwestern Iran studied fungal infections of skin, hair, and nails by identifying different types of dermatophytes from patient samples and soil. They found that a fungus called Trichophyton mentagrophytes was the most common cause, but also discovered a rare fungus called Myriodontium keratinophilum causing nail infections. Using modern DNA testing methods, they identified seven different dermatophyte species and several other soil fungi, providing important information about fungal infections in this region.

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Superficial Fungal Infections in the Pediatric Dermatological Population of Northern Poland

This study examined fungal skin infections in children and teens in Northern Poland over six years, finding that about 1 in 5 children tested had a fungal infection. Different types of fungal infections were more common at different ages—younger children more often had scalp infections, while teenagers more often had foot and nail infections. The study found that children living in rural areas had higher infection rates than those in cities, suggesting that environmental factors play an important role in fungal infection patterns.

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Spread of Antifungal-Resistant Trichophyton indotineae, United Kingdom, 2017–2024

A highly resistant fungal infection called Trichophyton indotineae is rapidly spreading throughout the United Kingdom. Originally from southern Asia, this fungus causes difficult-to-treat skin infections, particularly in the groin area, and resists standard antifungal medications in about three-quarters of cases. Since 2023, cases have spread from London to other parts of the UK and Ireland, and experts predict it will soon become the leading cause of ringworm in the country.

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Treatment and diagnostic challenges associated with the novel and rapidly emerging antifungal-resistant dermatophyte, Trichophyton indotineae

A new type of fungal infection called Trichophyton indotineae has emerged and spread globally, particularly from India. It causes widespread skin infections that are difficult to treat because the fungus resists common antifungal medications. Doctors and laboratories need to be aware of this infection to properly identify it and choose effective treatments, especially for patients with travel history to affected regions.

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