Disease: thrombosis

Purification and Biochemical Characterization of a Novel Fibrinolytic Enzyme from Culture Supernatant of Coprinus comatus

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Scientists discovered and purified a powerful enzyme from the medicinal mushroom Coprinus comatus that can dissolve blood clots and prevent dangerous blood vessel blockages. This enzyme works in two ways: it can directly break down clots and also activate the body’s natural clot-dissolving systems. The enzyme is much smaller and safer than current blood-thinning medications, making it a promising natural alternative for treating heart disease and stroke.

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Acute Kidney Failure and Myocarditis Triggered by Magic Mushroom Toxicity in a Patient With Prior Cocaine Exposure

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A middle-aged man who used magic mushrooms along with alcohol and LSD developed severe kidney failure and heart inflammation. He had previously used cocaine, which made his condition worse by promoting blood clots throughout his body. Despite dialysis treatment, his kidneys stopped working, he developed heart problems and blood clots in major blood vessels, and he unfortunately passed away. This case highlights how dangerous it can be to mix magic mushrooms with other drugs, especially for people with a history of cocaine use.

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Whey Proteins and Bioactive Peptides: Advances in Production, Selection and Bioactivity Profiling

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Whey, a liquid byproduct from cheese-making that was once considered waste, contains valuable proteins that can be broken down into smaller bioactive peptides. These peptides have numerous health benefits including antimicrobial, anti-inflammatory, and antioxidant properties, and can be used in functional foods and medicines. Researchers are developing advanced techniques to extract and produce these peptides more efficiently, and using computer models to predict which peptides will have specific health benefits.

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Proteases from Pleurotus spp.: Properties, Production and Biotechnological Applications

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Oyster and king oyster mushrooms produce powerful enzymes called proteases that can break down proteins. These enzymes have multiple uses including fighting parasitic infections in animals and plants, making cheese, dissolving blood clots, and being used in detergents and cosmetics. The mushrooms can be grown on agricultural waste, making this a sustainable and cost-effective way to produce these valuable enzymes.

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Diverse origins of fibrinolytic enzymes: A comprehensive review

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Blood clots can cause heart attacks and strokes, which are major causes of death worldwide. Currently used clot-dissolving drugs have significant drawbacks including short effectiveness periods and side effects. This review examines how fibrinolytic enzymes—naturally occurring proteins that dissolve blood clots—can be obtained from various sources, especially fermented foods like Japanese natto. These enzymes show promise as safer, cheaper alternatives that could be produced in large quantities for treating cardiovascular diseases.

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Mycosynthesis of Metal-Containing Nanoparticles—Synthesis by Ascomycetes and Basidiomycetes and Their Application

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Scientists have discovered that common fungi like mushrooms and molds can produce tiny nanoparticles that fight bacteria, kill cancer cells, and speed up chemical reactions. This fungal method is much cheaper, safer, and more environmentally friendly than traditional chemical production methods. The nanoparticles can be used in medical treatments, wound dressings, water purification, and farming as natural fertilizers and pesticides.

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The Genus Cordyceps Sensu Lato: Their Chemical Constituents, Biological Activities, and Therapeutic Effects on Air Pollutants Related to Lung and Vascular Diseases

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Cordyceps mushrooms have been used in traditional Chinese medicine for centuries and are now being studied scientifically for their potential health benefits. These mushrooms contain powerful compounds that may help protect our lungs from air pollution effects and support heart health. Recent clinical studies show promising results for treating conditions like COPD, asthma, and even improving athletic performance in healthy people.

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