Disease: Subcutaneous fungal infection

Simultaneous infection with Fusarium proliferatum and Prototheca wickerhamii localized at different body sites

An 81-year-old woman taking long-term steroid medication developed two different fungal skin infections on her hands simultaneously – one on the right hand from a moldy wooden frame and one on the left hand possibly from sewage exposure. Doctors identified both fungi through microscopy and genetic testing. She was successfully treated with an antifungal medication called voriconazole for four weeks and recovered completely.

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Basidiobolomycosis caused by a rare species – Basidiobolus meristosporus

A five-year-old girl developed large swollen lumps on her buttock and thigh that were initially thought to be tuberculosis or cancer. Doctors took a tissue sample and found it was caused by a rare fungus called Basidiobolus meristosporus. Using advanced DNA sequencing techniques, they identified the exact fungus species and treated her successfully with an antifungal medication called itraconazole, leading to complete healing within six weeks.

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