Disease: stroke

Lysergic Acid Diethylamide (LSD) and the Heart: Exploring the Potential Impacts of LSD on Cardiovascular Function

This review examines how LSD affects the heart and blood vessels. While some evidence suggests LSD might protect against heart disease by reducing inflammation and blood clots, acute use can dangerously raise heart rate and blood pressure, and cause blood vessel constriction. Regular low-dose use raises concerns about potential valve damage. More research is needed to understand the full cardiovascular safety of LSD before it can be considered for medical use.

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Health benefits of fish and fish by-products—a nutritional and functional perspective

Fish is an excellent food that provides many important nutrients like protein, omega-3 fatty acids, and vitamins that help protect our hearts, brains, and overall health. Different fish species offer various health benefits including protecting against heart disease, diabetes, obesity, and brain disorders. However, some fish can contain harmful contaminants like mercury, so choosing safer options like salmon and cod is important for children and pregnant women.

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Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

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From Microbes to Myocardium: A Comprehensive Review of the Impact of the Gut-Brain Axis on Cardiovascular Disease

Your gut bacteria play a surprising role in heart health through a communication network called the gut-brain axis. When the balance of gut bacteria is disrupted (dysbiosis), it can lead to heart disease, high blood pressure, and clogged arteries. Beneficial bacteria produce helpful compounds like short-chain fatty acids that reduce inflammation and protect blood vessels, while harmful bacteria produce compounds that increase heart disease risk. Simple interventions like eating more fiber, taking probiotics, managing stress, and exercising can help maintain a healthy gut microbiome and improve heart health.

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Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review

This review examines how plant-based compounds called phytochemicals can help prevent and manage heart disease. These compounds, found in foods like berries, nuts, tea, garlic, and whole grains, work through multiple mechanisms including reducing inflammation, lowering cholesterol, and improving blood vessel function. The review highlights that while pharmaceutical treatments exist, dietary approaches using phytochemical-rich foods offer a cost-effective and sustainable way to support heart health.

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Dietary Intake of Phytochemicals, Gut Microbiota, and Appetite Control

This research editorial highlights how plant-based foods rich in phytochemicals can improve gut health by promoting beneficial bacteria growth and supporting communication between the gut and brain. These dietary interventions show promise in helping control appetite, improve metabolism, and reduce the risk of diseases like obesity and type 2 diabetes. The studies suggest that personalized nutrition approaches based on individual microbiome profiles could offer more effective disease prevention and health maintenance strategies.

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Biosensors Based on Phenol Oxidases (Laccase, Tyrosinase, and Their Mixture) for Estimating the Total Phenolic Index in Food-Related Samples

This review discusses specialized sensors that can quickly measure the total amount of beneficial plant compounds (phenolics) in foods like tea, wine, coffee, and fruits. These biosensors use enzymes from mushrooms and other sources to detect phenolic compounds more efficiently than traditional methods. The sensors can be made more effective by using tiny materials called nanomaterials, which improve how well they work and how long they last.

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Diverse origins of fibrinolytic enzymes: A comprehensive review

Blood clots can cause heart attacks and strokes, which are major causes of death worldwide. Currently used clot-dissolving drugs have significant drawbacks including short effectiveness periods and side effects. This review examines how fibrinolytic enzymes—naturally occurring proteins that dissolve blood clots—can be obtained from various sources, especially fermented foods like Japanese natto. These enzymes show promise as safer, cheaper alternatives that could be produced in large quantities for treating cardiovascular diseases.

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Cerebral Hypoxia-Induced Molecular Alterations and Their Impact on the Physiology of Neurons and Dendritic Spines: A Comprehensive Review

This review explains how low oxygen levels in the brain damage nerve cells and their connection points (dendritic spines) through a cascade of molecular changes. The brain normally has protective mechanisms, but severe or prolonged hypoxia overwhelms these defenses, leading to memory loss and cognitive problems. Several molecular pathways and supporting cells called astrocytes and microglia can help protect neurons. Understanding these protective mechanisms may lead to new treatments for brain conditions caused by low oxygen, such as stroke.

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Conditional deletion of ROCK2 induces anxiety-like behaviors and alters dendritic spine density and morphology on CA1 pyramidal neurons

Researchers created mice with reduced ROCK2 protein in brain cells to understand how this protein affects behavior and brain structure. These mice showed anxiety-like behavior, avoiding open spaces and preferring darkness. The study found that ROCK2 affects the structure of dendritic spines, which are tiny branches on nerve cells that allow communication between neurons, particularly in the hippocampus region involved in learning and memory.

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