Disease: rhino-orbito-cerebral infection

Catastrophic Cerebral Infarctions in a Pediatric Patient with Acute Lymphoblastic Leukemia Due to Mucorales Infection

An 11-year-old girl with leukemia undergoing chemotherapy developed a severe fungal infection called mucormycosis caused by Lichtheimia ramosa. The infection spread rapidly from her sinuses to her eyes and brain, causing multiple blood clots in brain arteries and a massive stroke within just five days. Despite emergency surgery to remove the clots, the infection had progressed too far and the patient sadly did not survive, highlighting how dangerous this fungal infection can be in children with weakened immune systems.

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Epidemiology of mucormycosis in COVID-19 patients in northwest Iran: Rhizopus arrhizus as the predominant species

This study found that COVID-19 patients in northwestern Iran who received high-dose steroid treatment developed serious fungal infections called mucormycosis. The infection was caused primarily by a fungus called Rhizopus arrhizus and affected mainly the sinuses and brain. The steroids used to treat COVID-19 weakened patients’ immune systems and triggered diabetes, both of which made them vulnerable to this dangerous fungal infection.

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