Disease: Renal cell carcinoma

Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

This review examines how traditional Chinese medicine ingredients can boost the body’s natural ability to fight cancer when combined with tiny nanoparticles that deliver drugs more effectively. The nanoparticles help TCM compounds work better by improving how they dissolve, how long they stay in the body, and where they target. By activating immune cells like natural killer cells and dendritic cells while reducing immune-suppressing cells, this combination approach offers a promising new strategy for cancer treatment with fewer side effects.

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Tumor-associated macrophages in tumor progression and the role of traditional Chinese medicine in regulating TAMs to enhance antitumor effects

This review explains how tumor-associated macrophages (immune cells) can either fight or help cancer depending on their type. Traditional Chinese Medicine contains compounds that can reprogram these macrophages to fight cancer more effectively. By shifting macrophages from a cancer-supporting state to a cancer-fighting state, TCM treatments could enhance the body’s natural ability to combat tumors and reduce side effects of conventional cancer therapies.

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Assessment of the Antitumor Activity of Green Biosynthesized Zinc Nanoparticles as Therapeutic Agent Against Renal Cancer in Rats

Researchers created tiny zinc nanoparticles using an edible white mushroom through an environmentally friendly process. When tested in rats with kidney cancer, these nanoparticles significantly reduced tumor markers, protected kidney cells from oxidative damage, and triggered cancer cell death. The treatment improved kidney function and showed no toxic effects, suggesting it could be a promising new therapy for kidney cancer.

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