Disease: pythiosis

Drug repurposing to fight resistant fungal species: Recent developments as novel therapeutic strategies

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Fungal infections are becoming increasingly difficult to treat due to growing drug resistance, affecting millions of people worldwide each year. This research collection explores creative solutions by repurposing existing medications and developing new combination therapies that work better together against resistant fungal species. Studies show promising results combining common antibiotics like minocycline with antifungal drugs, and natural compounds from traditional medicine show potential for treating hard-to-treat infections like Candida and Aspergillus.

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A novel, cheap and easy preparing selective medium for isolation of Pythium species

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Scientists developed an affordable and effective way to grow and study harmful Pythium fungi that cause crop diseases and infections in animals. The new FANS medium uses inexpensive antibiotics that are safer and cheaper than previous methods, making it accessible to researchers worldwide, especially in developing countries. This advancement helps researchers better understand and develop treatments for diseases caused by Pythium species in both agriculture and medicine.

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Drug repurposing to fight resistant fungal species: Recent developments as novel therapeutic strategies

mycolabadmin

This editorial highlights the growing problem of fungal infections that resist current treatments, causing millions of deaths worldwide each year. Researchers are finding new ways to fight these resistant infections by repurposing existing drugs in new combinations and discovering novel compounds from natural sources. The collection of studies presented shows promising results using combinations like minocycline with antifungal drugs, natural compounds like baicalin, and AI technology to predict resistance patterns. These innovative approaches offer hope for better treatment options for patients suffering from serious fungal infections.

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A novel, cheap and easy preparing selective medium for isolation of Pythium species

mycolabadmin

Researchers have created an inexpensive and easy-to-use growth medium called FANS that effectively isolates disease-causing Pythium fungi from soil and water samples. Unlike expensive laboratory media containing toxic chemicals, FANS uses affordable pharmaceutical antibiotics costing about $11.55 per liter. This new medium successfully prevents contamination from other fungi and bacteria while promoting Pythium growth, making it especially valuable for scientists in developing countries studying plant diseases and pythiosis infections.

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