Pneumocystis pneumonia – Page 2

Polymerase Chain Reaction on Respiratory Tract Specimens of Immunocompromised Patients to Diagnose Pneumocystis Pneumonia: A Systematic Review and Meta-analysis

mycolabadmin

This study analyzed how well PCR tests detect Pneumocystis pneumonia, a serious fungal lung infection in immunocompromised patients. The research reviewed 55 studies with over 11,000 tests and found that PCR testing of fluid from the lungs or induced sputum works very well, especially at ruling out the disease when negative. However, positive test results need careful interpretation because the test can detect the fungus even when it’s just colonizing rather than causing active infection.

Assessing Diagnostic Capabilities and Treatment Accessibility for Invasive Fungal Infections in the Balkan Region

mycolabadmin

Researchers surveyed medical centers across 12 Balkan countries to understand how well-equipped they are to diagnose and treat serious fungal infections. They found that while most centers have basic laboratory tools like microscopes and cultures, advanced molecular tests for identifying fungal species are less common. Antifungal medications like triazoles are widely available, but other important treatment options are harder to find in the region.

Pneumocystis jirovecii is a potential pivotal ecological driver contributing to shifts in microbial equilibrium during the early-life lower airway microbiome assembly

mycolabadmin

Researchers studied how bacteria and fungi colonize infant lungs during the first year of life by examining lung tissue from autopsied infants. They found that the lung microbiome undergoes major changes between 2-4 months of age, and that a common fungal infection called Pneumocystis plays a key role in reshaping this microbial community. These early-life changes could have lasting impacts on children’s respiratory health later in life.

Fungal β-Glucans: Biological Properties, Immunomodulatory Effects, Diagnostic and Therapeutic Applications

mycolabadmin

β-glucans are natural substances found in yeast and fungi that help boost the immune system and fight cancer. They can be measured in blood to diagnose serious fungal infections and may help prevent common illnesses like colds and respiratory infections. Recent research suggests they could be useful additions to vaccines and may help patients recovering from COVID-19.

Incidence And Risk Factors for Invasive Fungal Infections in Pre-Transplant and Transplant-Ineligible Multiple Myeloma in the U.S.: A Claims Analysis (2017-2021)

mycolabadmin

This study examined fungal infections in patients with multiple myeloma who were not eligible for or preparing for stem cell transplants. Researchers found that 6% of these patients developed invasive fungal infections, with yeast infections being the most common type. The risk of these infections was significantly higher in patients taking dexamethasone (a steroid) or those with low white blood cell counts and those receiving multiple cancer therapies.

Disease: Pneumocystis pneumonia

Polymerase Chain Reaction on Respiratory Tract Specimens of Immunocompromised Patients to Diagnose Pneumocystis Pneumonia: A Systematic Review and Meta-analysis

Assessing Diagnostic Capabilities and Treatment Accessibility for Invasive Fungal Infections in the Balkan Region

Pneumocystis jirovecii is a potential pivotal ecological driver contributing to shifts in microbial equilibrium during the early-life lower airway microbiome assembly

Fungal β-Glucans: Biological Properties, Immunomodulatory Effects, Diagnostic and Therapeutic Applications

Incidence And Risk Factors for Invasive Fungal Infections in Pre-Transplant and Transplant-Ineligible Multiple Myeloma in the U.S.: A Claims Analysis (2017-2021)