Disease: photoaging

Benefits and risks of hair, skin, and nail supplements in older adults

This article reviews popular supplements that older adults, especially women, take to improve their hair, skin, and nails. While some supplements like nicotinamide show promise for sun-damaged skin, most lack strong evidence of benefit in healthy people. Important risks include biotin interfering with heart and thyroid tests, too much zinc causing copper deficiency, and excess vitamins A and E building up to toxic levels. Doctors should talk to older patients about these supplements and help them make informed decisions based on scientific evidence rather than marketing claims.

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The Benefits of a Multimechanistic Antiaging Skin Technology

Researchers tested a special antiaging face serum containing multiple skin-boosting ingredients on 50 women over 24 weeks. The serum significantly improved skin hydration, firmness, texture, and reduced wrinkles and fine lines. Results showed improvements as early as one week, with continued benefits throughout the study, and the product was very well tolerated with no irritation or side effects.

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Electrospun Membranes Loaded with Melanin Derived from Pecan Nutshell (Carya illinoinensis) Residues for Skin-Care Applications

Researchers developed new skincare membranes by combining pecan shell waste with advanced fiber technology. These membranes harness melanin from the shells to create materials with strong antioxidant and antibacterial properties that could protect skin from aging and infections. The innovation demonstrates how agricultural waste can be transformed into valuable cosmetic products that are both effective and environmentally friendly.

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Nomilin from Yuzu Seed Has In Vitro Antioxidant Activity and Downregulates Melanogenesis in B16F10 Melanoma Cells through the PKA/CREB Signaling Pathway

Scientists extracted a compound called nomilin from yuzu seeds and tested whether it could lighten skin by reducing melanin production. They found that nomilin works by blocking an enzyme called tyrosinase that makes melanin, and it reduces the activity of cell signaling pathways involved in skin darkening. The study shows nomilin could be used as a natural skin-whitening ingredient in cosmetics without the side effects of synthetic alternatives.

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Assessment of Cucurbita spp. Peel Extracts as Potential Sources of Active Substances for Skin Care and Dermatology

This study examined pumpkin peels as a sustainable source of natural compounds for skincare products. Researchers extracted active ingredients using water and plant-based solvents, then tested their antioxidant properties, ability to protect skin from sun damage, and safety for use on skin. The findings show that pumpkin peel extracts, particularly those made with water, could be safe and effective ingredients in cosmetic products.

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Evaluation of Salvia yangii Extract as a Promising Protective Raw Material Applied Topically to the Skin

Russian Sage (Salvia yangii) extract shows promise as a natural ingredient for skincare products. The study found that the plant contains compounds like rosmarinic acid that provide antioxidant, antimicrobial, and anti-aging benefits. When used at appropriate concentrations, the extract protected skin cells from sun damage and helped inhibit enzymes that break down skin collagen. This research supports the use of S. yangii in developing safer, more effective natural cosmetic products.

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Skin Improvement with Antioxidant Effect of Yuja (Citrus junos) Peel Fractions: Wrinkles, Moisturizing, and Whitening

Yuja, a citrus fruit traditionally used in Asian medicine, shows promising benefits for skin health. This study found that extracts from Yuja peels can help reduce wrinkles, improve skin moisture, and lighten dark spots by protecting skin cells from UV damage and reducing harmful free radicals. The effects work through natural mechanisms that boost collagen production and inhibit melanin overproduction, making Yuja peel fractions promising ingredients for new skincare products.

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Safe and Effective Antioxidant: The Biological Mechanism and Potential Pathways of Ergothioneine in the Skin

Ergothioneine is a natural compound found in certain fungi and bacteria that acts like a powerful antioxidant in the body. When applied to skin, it can protect against damage from sun exposure and environmental pollution, reduce signs of aging, and help calm inflammation. It’s particularly special because it automatically travels to damaged areas in the skin where it’s needed most, making it an efficient and targeted treatment ingredient for cosmetics.

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