Disease: oxidative stress

Optimized Extraction of Bioactive Polysaccharides from Wild Mushrooms: Toward Enhanced Yield and Antioxidant Activity

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Scientists optimized how to extract healthy compounds called polysaccharides from three wild mushroom species found in European forests. Using hot water extraction with carefully controlled temperature, time, and water amounts, they found that each mushroom type had different optimal conditions for getting the most beneficial compounds. The extracted polysaccharides showed strong antioxidant properties and could be used to develop new functional foods or supplements.

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Hypoglycemic Effect of Pleurotus citrinopileatus and Hericium erinaceus Buccal Tablets on Diabetic Mice

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Researchers created special tablets from two edible mushrooms (yellow oyster mushroom and lion’s mane) enriched with trace elements (chromium, zinc, germanium) to treat diabetes in mice. After three weeks of treatment, the high-dose tablets reduced blood sugar levels by 29%, improved cholesterol levels, boosted the body’s natural antioxidant defenses, and shifted the gut bacteria toward beneficial types that support metabolic health. These results suggest that mushroom-based treatments could potentially offer a natural way to help manage diabetes.

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Modulating effects of Phellinus linteus polysaccharides on antioxidant capacity, immune function, intestinal function and microbiota in lipopolysaccharide-challenged broilers

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Researchers studied how a medicinal mushroom extract called Phellinus linteus polysaccharides could help broiler chickens recover from immune stress caused by bacterial toxins. The supplement improved the chickens’ growth, reduced harmful inflammatory responses, and promoted beneficial gut bacteria while reducing harmful ones. The treatment strengthened the intestinal barrier and restored the chickens’ natural antioxidant defenses. This suggests the mushroom supplement could be a natural alternative to antibiotics for improving poultry health on farms.

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Native Fungi as a Nature-Based Solution to Mitigate Toxic Metal(loid) Accumulation in Rice

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Rice farmers dealing with contaminated soils now have a natural solution: specially selected fungi can be added to the soil to help reduce toxic metal accumulation in rice plants. In a greenhouse study, native fungi reduced arsenic uptake by up to 75% when combined with specific water management practices. This approach offers an environmentally friendly alternative to traditional remediation methods while promoting sustainable agriculture in metal-contaminated areas.

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Strategies for Enhancing Resilience in Horticultural Crops Against Combined Abiotic Stresses

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As climate change brings more extreme weather, vegetable and fruit crops face multiple environmental challenges simultaneously, like drought, high salt content, and heat. Scientists have developed practical approaches to make these crops stronger, including breeding tougher varieties, grafting plants onto hardy rootstocks, and applying special nanoparticles and natural plant boosters. These combined strategies help crops survive harsh conditions while maintaining good yields and quality, supporting food security for growing populations worldwide.

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Development of Hybrid Pleurotus cystidiosus Strains with Enhanced Functional Properties

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Scientists created new hybrid varieties of abalone mushrooms by breeding two different strains together. These new hybrids produced more health-beneficial compounds like antioxidants and fiber-like polysaccharides than their parent strains. Two particularly promising hybrids, PA-132 and PA-054, showed the strongest antioxidant properties and could potentially be developed into functional food products for health and wellness applications.

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Chemical Characterization and In Vitro Antioxidant, Anti-Inflammatory, and Colon Cancer-Preventive Potential of a Polysaccharide Fraction from Macrolepiota procera

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Researchers isolated special sugar compounds called polysaccharides from parasol mushrooms and tested their health benefits. These compounds were found to fight free radicals that damage cells, reduce inflammation in the body, and specifically kill colon cancer cells while leaving healthy cells unharmed. The study suggests that parasol mushrooms could be developed into health supplements or functional foods to help prevent cancer and improve overall health.

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