Disease: oxidative stress-related diseases

In vitro assessment of multipotential therapeutic importance of Hericium erinaceus mushroom extracts using different solvents

This research examined how Lion’s Mane mushroom extracts made with different liquids can fight infections and oxidative damage. The water-based extract was best at preventing viruses and free radical damage, while the ethyl acetate extract worked best against bacteria and fungi. The study identified 16 beneficial compounds in the mushroom and suggests it could be used as a daily supplement to protect against infections and oxidative stress.

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Structural Elucidation, Modification, and Structure-Activity Relationship of Polysaccharides in Chinese Herbs: A Review

This comprehensive review explains how the structure of plant polysaccharides from Chinese herbs determines their healing properties. The authors discuss various laboratory methods to identify polysaccharide structures and explain how chemical modifications can enhance their beneficial effects like boosting immunity and fighting tumors. The review provides guidance for researchers developing new polysaccharide-based medicines and shows that finding the right molecular size and chemical composition is key to maximizing therapeutic benefits.

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Biphasic Fermentation of Trapa bispinosa Shells by Ganoderma sinense and Characterization of Its Polysaccharides and Alcoholic Extract and Analysis of Their Bioactivity

This study investigated fermenting water chestnut shells with a medicinal mushroom called Ganoderma sinense to create a more potent health product. Under optimal fermentation conditions, the resulting material showed significantly improved immune-boosting and antioxidant properties when tested in laboratory cells. The fermentation process changed the structure of polysaccharides and increased beneficial compounds, potentially transforming agricultural waste into a valuable functional food or supplement.

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Biological Characteristics, Domesticated Cultivation Protocol, Antioxidant Activity, and Protective Effects against Cellular Oxidative Stress of an Underutilized Medicinal Mushroom: Fomitopsis palustris

Researchers successfully grew and studied Fomitopsis palustris, a medicinal mushroom, in laboratory conditions. They discovered that the mushroom contains beneficial compounds that protect cells from damage caused by harmful free radicals. The polysaccharides extracted from the mushroom boosted the cells’ natural defense systems and reduced oxidative stress markers, suggesting potential health benefits for treating age-related and degenerative diseases.

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Investigating the Neuroprotective, Hepatoprotective, and Antimicrobial Effects of Mushroom Extracts

This study examined four types of edible mushrooms to see if they could protect against aging and fight harmful bacteria. Researchers gave mice an aging-inducing substance and then treated them with mushroom extracts. The mushrooms, particularly Lion’s Mane (Hericium erinaceus), helped prevent brain and liver damage, reduced inflammation, and showed antibacterial effects against multiple bacterial strains. These findings suggest mushrooms could be useful natural supplements to promote health and combat age-related decline.

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Bioactive Potential of Balkan Fomes fomentarius Strains: Novel Insights into Comparative Mycochemical Composition and Antioxidant, Anti-Acetylcholinesterase, and Antiproliferative Activities

This study examines three strains of Fomes fomentarius mushroom from the Balkan region, revealing they are rich sources of beneficial compounds including polyamines and phenolic compounds. These extracts demonstrated strong antioxidant properties and potential neuroprotective effects, suggesting they could help prevent diseases related to oxidative stress and aging. The research supports the traditional use of this mushroom in folk medicine and highlights its potential as a natural supplement for health promotion.

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Ultrasound-assisted extraction and antioxidant activity of polysaccharides from Tenebrio molitor

Researchers successfully extracted beneficial compounds called polysaccharides from mealworms (Tenebrio molitor) using ultrasound waves, making the process faster and more efficient than traditional methods. These extracted polysaccharides demonstrated strong antioxidant properties, meaning they can help neutralize harmful free radicals in the body. The study shows that mealworm polysaccharides could be used as natural health supplements or food additives with health benefits comparable to or better than Vitamin C.

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Enhancement of polysaccharides production using microparticle enhanced technology by Paraisaria dubia

Researchers developed a new method to produce medicinal polysaccharides from a Cordyceps fungus using tiny talc particles to improve fermentation. By adding the right amount and size of talc particles, they were able to produce significantly more polysaccharides with beneficial health properties. The method works well in large-scale bioreactors and could be used to produce these valuable medicinal compounds more efficiently.

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Polysaccharides from fungi: A review on their extraction, purification, structural features, and biological activities

Mushrooms contain special compounds called polysaccharides that have powerful health benefits. Scientists have found these polysaccharides can help fight cancer, boost immunity, reduce inflammation, and manage diabetes. This review explains different ways to extract and purify these beneficial compounds from mushrooms and describes how they work in the body to provide these health benefits.

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