Disease: obesity

Fermented Rice Bran: A Promising Therapeutic Agent Against High-Fat Diet-Induced Metabolic Disorders

Fermented rice bran, created by fermenting rice byproduct with beneficial bacteria, shows promise in helping manage weight and blood sugar levels in studies using rats on high-fat diets. The fermentation process increases the nutritional value of rice bran by boosting protein, fiber, and antioxidant content. Animals supplemented with fermented rice bran for 8 weeks showed improved cognitive function, better liver health, and improved lipid profiles compared to those on high-fat diets alone.

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Physicochemical properties and fermentation characteristics of a novel polysaccharide degraded from Flammulina velutipes residues polysaccharide

Researchers developed a new method to break down a large mushroom polysaccharide from golden needle mushroom plant residues into smaller, more useful molecules. The smaller version works better as an antioxidant and helps feed beneficial gut bacteria, producing beneficial compounds that support digestive health. This discovery could lead to new functional food products and health supplements using mushroom waste that would otherwise be discarded.

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The Role of Wolfiporia cocos (F. A. Wolf) Ryvarden and Gilb. Polysaccharides in Regulating the Gut Microbiota and Its Health Benefits

Wolfiporia cocos, a fungus used in traditional Chinese medicine for over 2000 years, contains polysaccharides that act as prebiotics to improve gut health. These polysaccharides promote the growth of beneficial bacteria while inhibiting harmful ones, increase production of healthy metabolites, and strengthen the intestinal barrier. By improving gut microbiota composition, these polysaccharides can help prevent and treat various diseases including obesity, diabetes, and inflammatory conditions.

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Targeting the AMP-activated protein kinase pathway: the active metabolites of botanical drugs represent potential strategies for treating metabolic-associated fatty liver disease

Fatty liver disease is becoming increasingly common and current medications have side effects like dangerously low blood sugar. This review shows that natural plant-based compounds and traditional Chinese herbs can activate a key protein (AMPK) in the body that helps burn fat and regulate sugar levels. Over 30 different plant compounds from foods and herbs like ginger, curcumin, and ganoderma mushrooms have been shown to improve fatty liver disease by activating this protein through multiple beneficial mechanisms.

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Domestication Cultivation and Nutritional Analysis of Hericium coralloides

Researchers successfully grew a rare medicinal mushroom called Hericium coralloides from a wild sample found on the Tibetan Plateau. The mushroom is nutrient-rich, containing good amounts of protein and fiber while being low in fat, making it a healthy food choice. The mushroom’s compounds showed strong antioxidant properties and the ability to slow the growth of certain cancer cells, particularly breast cancer cells, suggesting potential health benefits.

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Evaluation of Lipid Changes During the Drying Process of Cordyceps sinensis by Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS)-Based Lipidomics Technique

This study examines how different drying methods affect the lipid content of Cordyceps sinensis, a valuable medicinal mushroom. Researchers compared three drying techniques—freeze-drying, oven-drying, and air-drying—and found that freeze-drying best preserves the mushroom’s beneficial lipids, while oven-drying causes significant degradation. The findings provide practical guidance for mushroom producers on selecting optimal drying methods to maintain the medicinal quality and nutritional value of this prized fungus.

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Effects of Monascus pilosus SWM 008-Fermented Red Mold Rice and Its Functional Components on Gut Microbiota and Metabolic Health in Rats

Researchers studied whether fermented red mold rice could improve gut health in rats by examining changes in beneficial bacteria. The study found that red mold rice and its active compounds increased helpful bacteria like Akkermansia mucinophila without causing any harmful effects. These beneficial bacteria may support better digestion, metabolism, and overall health, suggesting fermented red mold rice could be useful as a functional food for maintaining a healthy gut.

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Factors governing consumers buying behavior concerning nutraceutical product

This study examines why people buy nutraceutical products like health supplements and functional foods. Key factors include knowing the health benefits, product taste and packaging, affordability and availability, and recommendations from healthcare professionals. The study found that age, education, and gender affect purchasing decisions, and online shopping has become increasingly important. Companies should focus on innovative products with simple health messages to better serve different consumer groups.

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The release patterns and potential prebiotic characteristics of soluble and insoluble dietary fiber-bound polyphenols from pinot noir grape pomace in vitro digestion and fermentation

This study examined how grape pomace dietary fiber and its bound polyphenols are broken down in the digestive system and colon. Researchers found that soluble fiber was particularly effective at releasing beneficial compounds that feed healthy gut bacteria and produce short-chain fatty acids important for health. The fiber types promoted beneficial bacteria like Bifidobacterium while reducing harmful bacteria, suggesting grape pomace could be a valuable ingredient in functional foods to support digestive and overall health.

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Galacto-Oligosaccharides Exert Bifidogenic Effects at Capsule-Compatible Ultra-Low Doses

This study tested whether tiny doses of a prebiotic called galacto-oligosaccharides (GOS) could be effective when taken in capsule form instead of large sachets. Researchers used a specially designed laboratory system to simulate how these compounds work in the human gut. Even at the lowest dose tested (0.5 g), the GOS successfully increased beneficial gut bacteria and produced helpful compounds that support digestive health, while producing minimal gas.

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