Disease: obesity

Molecular Identification, Mycelial Growth Kinetics, and Antimicrobial Potential of Newly Isolated Medicinal Mushroom Fomitopsis pinicola from Bulgaria

Scientists isolated and studied a medicinal mushroom called Fomitopsis pinicola from Bulgaria. They confirmed its identity using DNA analysis and tested how well it grows on different nutrient media. The mushroom showed strong antimicrobial effects against disease-causing bacteria, especially when extracted with water, making it a promising candidate for developing new antibiotics to fight antibiotic-resistant infections.

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Anti-Obesity Effect of Chitoglucan in High-Fat-Induced Obesity Mice

A natural compound called chitoglucan extracted from enoki mushrooms (Flammulina velutipes) was found to reduce weight gain and body fat in mice fed a high-fat diet. The treatment worked by lowering levels of hormones called leptin and resistin that are elevated in obesity. This suggests that chitoglucan from enoki mushrooms could potentially help treat obesity and related metabolic disorders in humans.

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A screen for sleep and starvation resistance identifies a wake-promoting role for the auxiliary channel unc79

Scientists conducted a genetic screening study in fruit flies to understand how sleep and the body’s ability to survive without food are connected. They discovered that a gene called unc79 plays an important role in promoting wakefulness and affecting how long flies can survive starvation. Interestingly, this gene works in a brain region called the mushroom body and functions differently there than it does in controlling daily biological rhythms. These findings help explain how sleep and metabolism are linked, which could have implications for understanding human sleep disorders and metabolic diseases.

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The Benefits and Applications of Lactobacillus plantarum in Food and Health: A Narrative Review

Lactobacillus plantarum is a beneficial bacterium commonly found in fermented foods like yogurt and cheese that acts as a natural probiotic. It can help preserve food, improve flavor, and boost health by supporting digestion, strengthening immunity, and reducing inflammation. Research shows it may help with weight management, blood sugar control, and mental health, making it valuable for both the food industry and medical applications.

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A Rare Case of Methyldopa-Induced Hepatitis

A 31-year-old woman developed severe liver inflammation (hepatitis) six weeks after starting methyldopa, a common blood pressure medication. After stopping the drug, her liver function returned to normal without needing steroids or other intensive treatments. This case reminds doctors that even commonly used, safe medications can rarely cause serious liver problems and should be considered when patients develop unexplained liver inflammation.

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The rise of Stropharia rugosoannulata industry in China: current state and prospects

The wine-cap mushroom (Stropharia rugosoannulata) is becoming a major agricultural industry in China with over 494,000 tons produced annually. This large, meaty mushroom is rich in proteins, minerals, and healing compounds that may help fight diabetes, obesity, and heart disease. It grows easily on agricultural waste materials, making it an environmentally friendly crop that’s being used to help rural communities and reduce farming pollution.

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Fungal β-Glucans: Biological Properties, Immunomodulatory Effects, Diagnostic and Therapeutic Applications

β-glucans are natural substances found in yeast and fungi that help boost the immune system and fight cancer. They can be measured in blood to diagnose serious fungal infections and may help prevent common illnesses like colds and respiratory infections. Recent research suggests they could be useful additions to vaccines and may help patients recovering from COVID-19.

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Bibliometric, taxonomic, and medicinal perspectives of Ganoderma neo-japonicum Imazeki: A mini review

Ganoderma neo-japonicum, known as purple Lingzhi, is a mushroom traditionally used by indigenous communities in Malaysia and other Asian countries to treat various health conditions. This review examines 36 scientific studies published between 1991 and 2021, showing that the mushroom contains special compounds that can fight cancer cells, lower blood sugar, reduce inflammation, and boost immunity. While laboratory studies show promising results, the mushroom still needs more clinical testing in humans before it can be widely used as a medicine.

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Epigenome-wide association study of BMI and waist-to-hip ratio and their associations with dietary patterns in Korean adults

This research examined how different types of obesity (overall body weight versus belly fat) are associated with changes in DNA methylation patterns in Korean adults. The study found that certain DNA regions become less methylated in obese individuals, and that these epigenetic changes are linked to different dietary patterns. The findings suggest that specific foods may influence these epigenetic modifications differently depending on whether someone has overall obesity or more belly fat, opening new possibilities for using diet to prevent or manage obesity.

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Optimizing and Characterization of Soybean Oil Seed Cake Protein Hydrolysis: In Vitro Analysis

Researchers successfully created a high-protein powder from soybean processing waste by breaking down proteins using special enzymes. The resulting powder contains 60% protein and shows promising health benefits including antioxidant properties and the ability to slow glucose absorption, making it potentially useful for managing diabetes and obesity. This converts a low-value agricultural byproduct into a valuable ingredient for food and pharmaceutical applications.

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