Disease: obesity

Physicochemical and Sensory Properties of Pork Patties with Partial Replacement of Lean Pork by Stalks of Agaricus bisporus

Researchers developed healthier pork patties by replacing up to 50% of the meat with mushroom stalks (Agaricus bisporus). The resulting patties had less fat and more fiber while maintaining good taste and texture. However, very high replacement levels (more than 50%) reduced protein quality. This approach helps reduce food waste from mushroom processing while creating more nutritious meat products.

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Cross-cohort microbiome-wide study reveals consistent alterations in the gut bacteriome, but not the gut mycobiome, in patients with hypertension

Researchers analyzed gut bacteria and fungi in hypertensive patients compared to healthy people across two regions in China. They found that hypertensive patients have significant changes in their gut bacteria, particularly an overgrowth of harmful species like Clostridium and a decrease in beneficial bacteria. Interestingly, fungi in the gut showed minimal differences. These bacterial changes could potentially be used as early warning signs for hypertension and might become targets for new treatments.

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Chitosan and Chitooligosaccharide: The Promising Non-Plant-Derived Prebiotics with Multiple Biological Activities

Chitosan and chitooligosaccharide are natural compounds derived from crustacean shells and fungi that act as prebiotics to improve gut health. These compounds can fight bacteria and viruses, reduce inflammation, protect against oxidative stress, and help maintain healthy weight and blood sugar levels. They represent a promising, biodegradable alternative to synthetic pharmaceuticals with multiple health benefits.

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Novel Approaches in Glucose and Lipid Metabolism Disorder Therapy: Targeting the Gut Microbiota–Bile Acid Axis

Your gut bacteria play a key role in how your body manages blood sugar and fats, working through molecules called bile acids. Researchers have discovered that certain foods, supplements, and herbs can improve this gut bacteria-bile acid interaction to help prevent or treat diabetes and obesity. This review explains how these natural interventions work and suggests promising new ways to treat metabolic diseases by harnessing your gut health.

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Effect of soluble dietary fiber from corn bran on pasting, retrogradation, and digestion characteristics of corn starch

Researchers found that adding a special fiber derived from corn bran to corn starch significantly improves its properties for food production. The fiber helps prevent the starch from hardening over time, reduces how quickly the body digests it (important for controlling blood sugar), and improves texture and water retention. This discovery could help create healthier starch-based foods and better products for people with swallowing difficulties.

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Human Gut Microbiome: A Connecting Organ Between Nutrition, Metabolism, and Health

Your gut bacteria function like an extra organ, helping digest food and producing important compounds that affect your whole body. The type of bacteria in your gut depends on diet, delivery method at birth, and antibiotics you’ve taken. Eating more fiber and taking certain probiotics can improve your bacterial balance and help prevent diseases like diabetes, obesity, and heart problems. This suggests that managing your gut microbiome through diet might be just as important as taking traditional medicines for staying healthy.

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The effect of chitosan supplementation on liver function, hepatic steatosis predictors, and metabolic indicators in adults with non-alcoholic fatty liver disease: a randomized, double-blinded, placebo-controlled, clinical trial

This study tested whether taking chitosan supplements (a type of dietary fiber) helps people with fatty liver disease. Over 8 weeks, participants taking chitosan along with a calorie-reduced diet lost more weight, reduced their waist size, and showed improvement in liver enzyme levels compared to those taking placebo. However, the supplement did not significantly improve cholesterol, blood sugar, or other metabolic markers at the dose tested.

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Exploring the relationship between dietary patterns and health-related quality of life among Iranian adult population: Tehran lipid and glucose study

This study examined how different eating patterns affect people’s overall quality of life in Iran. Researchers found that people who eat more vegetables, fruits, legumes, and lean proteins report better physical and mental health. In contrast, diets high in processed foods, red meat, and sweets were associated with worse mental health in men. Interestingly, the benefits of healthy eating appeared stronger in women than men, suggesting that gender may influence how diet affects quality of life.

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Characterization of the gut mycobiome in patients with non-alcoholic fatty liver disease and correlations with serum metabolome

This research reveals that the types of fungi living in our gut are linked to fatty liver disease in ways we didn’t fully understand before. While researchers have long studied bacteria in our gut, they largely ignored fungi, which turns out to play an important role too. The study found that certain fungal species are more common in people with fatty liver disease, and these fungi influence the metabolites (chemical compounds) in the blood that affect liver health. By combining information about fungi, bacteria, and blood chemistry, scientists developed a test that could identify fatty liver disease with 77% accuracy, suggesting that looking at gut fungi could help doctors diagnose and treat this common liver condition.

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