Disease: neurodegenerative disorders

Unveiling roles of beneficial gut bacteria and optimal diets for health

Your gut bacteria are tiny living organisms that help digest food, support your immune system, and influence your overall health. Eating foods rich in fiber, fermented products like yogurt and kimchi, and colorful fruits and vegetables helps grow these beneficial bacteria. When your gut bacteria become unbalanced, it can lead to inflammation and various diseases, but eating the right foods can restore balance and improve your health.

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Exploring the Nutritional Value and Bioactive Potential of Craterellus cornucopioides (L.) Pers. as a Functional Food Source

Black trumpet mushrooms from Romania have been found to contain high levels of beneficial compounds that protect cells from damage and fight harmful bacteria. The mushrooms showed strong antioxidant properties in laboratory tests and were effective against several disease-causing bacteria, though not against all types tested. These results suggest that black trumpets could be used as a natural supplement or food ingredient to support health and potentially help treat infections.

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Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management

This review explains how scientists use computer simulations to understand how natural food compounds (called nutraceuticals) interact with disease-causing molecules in the body. By using molecular docking software, researchers can predict which compounds might fight diseases like cancer and heart disease before conducting expensive laboratory tests. The review shows that many common foods like turmeric, grapes, and green tea contain compounds that could potentially treat various diseases by targeting specific proteins and pathways involved in disease development.

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The Effect of 2′-Fucosyllactose on Gut Health in Aged Mice

This research shows that 2′-fucosyllactose, a natural compound found in breast milk, can significantly improve gut health in older mice. The treatment strengthened the intestinal barrier, reduced harmful inflammation, and increased beneficial bacteria populations. These findings suggest that 2′-FL could be developed as a food supplement to help older people maintain better digestive and immune health.

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The microbial strategies for the management of chemical pesticides: A comprehensive review

Chemical pesticides used to protect crops contaminate soil and water, harming both ecosystems and human health. Scientists have discovered that specific microorganisms—bacteria, fungi, and algae—can naturally break down these harmful pesticides into harmless substances. By using advanced technologies to understand how these microbes work and even genetically enhancing them, researchers are developing sustainable solutions to clean up pesticide-contaminated environments without the toxic side effects of traditional cleanup methods.

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Harnessing mushrooms for poultry nutrition: Boosting health, immunity, and productivity

Mushrooms and mushroom stems are emerging as natural feed additives that can significantly improve poultry health, growth, and egg/meat quality while reducing the need for antibiotics. These fungi contain beneficial compounds that boost immune function, reduce harmful bacteria, and protect against cellular damage. By using mushroom byproducts that are typically discarded, farmers can create more sustainable and environmentally friendly poultry production systems while improving overall bird health and productivity.

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Bioactive Compounds and Antioxidant Activity of Boletus edulis, Imleria badia, Leccinum scabrum in the Context of Environmental Conditions and Heavy Metals Bioaccumulation

This study examined three popular edible mushroom species from Poland to understand their nutritional benefits and safety. While all three mushrooms are rich in beneficial compounds like antioxidants and immune-boosting polysaccharides, Boletus edulis (porcini) accumulates concerning levels of cadmium from soil. The research shows these mushrooms are safe in normal amounts, but eating excessive quantities of porcini mushrooms could exceed safe limits for toxic metals, especially for people in polluted areas.

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Unveiling the Therapeutic Potentials of Mushroom Bioactive Compounds in Alzheimer’s Disease

Mushrooms contain special compounds that may help protect the brain from Alzheimer’s disease. Research shows that eating mushrooms regularly could reduce the risk of memory problems and cognitive decline in older adults. These compounds work by reducing brain inflammation, protecting nerve cells, and helping the brain clear out harmful proteins. While these findings are promising, more human studies are needed to confirm how effective mushrooms are as an Alzheimer’s treatment.

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Emerging paradigms for target discovery of traditional medicines: A genome-wide pan-GPCR perspective

Traditional medicines from plants, animals, and fungi contain chemical compounds that can interact with specific proteins in our cells called G protein-coupled receptors (GPCRs). These receptors control many important body functions and are targeted by about one-third of all FDA-approved medications. This review explains how scientists are discovering new therapeutic compounds from traditional medicines by systematically screening them against the complete library of human GPCRs, using advanced techniques to identify which compounds bind to which receptors. Famous examples include morphine from poppies for pain relief and compounds from ginseng that help regulate blood sugar.

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Exploring the Potential of Haematococcus pluvialis as a Source of Bioactives for Food Applications: A Review

Haematococcus pluvialis is a tiny green algae that produces astaxanthin, a powerful natural antioxidant that gives it a bright red color when stressed. Beyond astaxanthin, this microalga is rich in proteins, healthy fats, and vitamins, making it useful for creating functional foods and supplements. Researchers are developing better ways to grow this algae and extract its beneficial compounds using environmentally friendly methods, with potential applications in foods ranging from beverages to meat alternatives.

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