Disease: neurodegenerative diseases

Psychedelic Drugs or Hallucinogens: Exploring Their Medicinal Potential

Psychedelic drugs like LSD and psilocybin are substances that alter perception and consciousness. Research shows they may help treat serious mental health conditions including depression, anxiety, and PTSD by affecting how the brain forms new connections. These substances are relatively safe compared to many legal drugs, and scientists believe they could revolutionize mental health treatment when used properly under medical supervision.

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Isolation and Evaluation of Erinacine A Contents in Mycelia of Hericium erinaceus Strains

Researchers developed a new method to extract and purify erinacine A, a beneficial compound from lion’s mane mushrooms, using an advanced separation technique called high-speed countercurrent chromatography. They tested 15 different mushroom strains and found that a wild strain called HeG produced significantly more erinacine A than commercially cultivated varieties. Erinacine A shows promise for protecting brain health and potentially helping with diseases like Alzheimer’s and Parkinson’s. This discovery could help make erinacine A supplements more accessible and affordable for consumers.

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Special Issue: Marine-Derived Compounds Applied in Cardiovascular Disease

This collection of studies explores how compounds from ocean sources like seaweed, fish, shrimp, and microalgae can help protect heart health and prevent cardiovascular diseases. Researchers examined various marine ingredients and found they can reduce inflammation, lower cholesterol, reduce blood pressure, and prevent blood clots. The findings suggest that marine-derived products could become safer, more affordable alternatives or complements to current heart disease medications while supporting sustainable ocean resource use.

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Antioxidant activity and phytochemical analysis of different varieties of barley (Hordeum vulgare L.) available in Pakistan

Researchers analyzed five varieties of barley grown in Pakistan to determine their nutritional and health benefits. They found that all varieties contained beneficial compounds with antioxidant properties, with Jau-21 performing exceptionally well. These barley varieties are rich in protein, fiber, minerals, and compounds that may help protect against diseases like diabetes and heart disease, making them promising ingredients for developing healthy food products.

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Quercetin hybrid-hydrogel microparticles modulate gut microbiota and improve memory in an antibiotic-induced dysbiosis rat model

A natural quercetin supplement formulated with fenugreek fiber was tested on rats with antibiotic-damaged gut bacteria. The supplement successfully restored healthy gut bacteria diversity, reduced gut inflammation, and improved memory performance. These benefits likely work through the gut-brain connection, where healthy bacteria produce beneficial chemicals that support brain function and reduce inflammation.

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Streptomyces antarcticus sp. nov., isolated from Horseshoe Island, Antarctica

Scientists discovered a new type of bacteria called Streptomyces antarcticus in Antarctic soil that can survive extreme cold and produce valuable compounds. This bacterium can make antibiotics, cancer-fighting molecules, and other useful substances, making it potentially useful for medicine and industry. The bacteria also has genes to break down pharmaceutical pollutants and adapt to harsh conditions, suggesting applications in cleaning up contaminated environments.

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Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

This study shows how adding olive mill waste to mushroom growing substrate can increase beneficial compounds in mushrooms while reducing harmful toxins. Researchers grew two types of edible mushrooms (lion’s mane and king oyster) on substrate containing different amounts of olive mill waste and used advanced chemical analysis to identify how the waste affected the mushrooms’ medicinal compounds. Adding olive mill waste increased healthy compounds like hericenones and erinacerins while decreasing toxic enniatin compounds, potentially creating safer and more nutritious mushrooms for consumers.

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Dissecting the difference between positive and negative brain health sentiment using X data

This study examined over 390,000 posts on X (formerly Twitter) about brain and health to understand how people express positive and negative feelings. Researchers found that negative posts were shared more often and were linked to serious health concerns like COVID-19 and brain inflammation. People expressing negative sentiment mentioned medications like lorazepam and comfort foods like pizza, while those with positive sentiment discussed resilience, mindfulness, and different medications. The research highlights both the benefits and dangers of sharing health information on social media.

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Scrutinizing the Nutritional Aspects of Asian Mushrooms, Its Commercialization and Scope for Value-Added Products

Mushrooms are nutrient-dense foods that can help address malnutrition and provide health benefits comparable to meat and eggs. They contain proteins, vitamins, minerals, and special compounds that help fight inflammation, boost immunity, and prevent diseases like cancer and heart disease. Mushroom-based products like powders, capsules, and fortified foods are becoming increasingly available in markets, offering practical ways to incorporate these nutritional benefits into daily diets.

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Enhancing Environmental and Human Health Management Through the Integration of Advanced Revitalization Technologies Utilizing Artificial Intelligence

This paper describes how combining artificial intelligence with environmental monitoring can help us better understand how pollution harms our health. The authors propose a seven-step system that collects data on pollution levels in air, water, and soil alongside health information from communities. By using AI to analyze these massive datasets together, scientists and doctors can more quickly identify which pollutants are causing specific health problems and design better treatments for affected people and environments.

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