Disease: Nasopharyngeal carcinoma

Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

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This review examines how traditional Chinese medicine ingredients can boost the body’s natural ability to fight cancer when combined with tiny nanoparticles that deliver drugs more effectively. The nanoparticles help TCM compounds work better by improving how they dissolve, how long they stay in the body, and where they target. By activating immune cells like natural killer cells and dendritic cells while reducing immune-suppressing cells, this combination approach offers a promising new strategy for cancer treatment with fewer side effects.

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Recent Advances in the Use of Ganoderma lucidum and Coriolus versicolor Mushrooms to Enhance the Anticancer Efficacy of EGFR-Targeted Drugs in Lung Cancer

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This review explores how two medicinal mushrooms traditionally used in Asian medicine—Lingzhi and Yunzhi—can enhance the effectiveness of lung cancer drugs (EGFR-TKIs) and help overcome drug resistance. These mushrooms contain special compounds that can fight cancer in multiple ways, boost the immune system, and reduce side effects. The research suggests that combining these mushrooms with standard cancer treatments may improve outcomes for lung cancer patients.

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Methods for Overcoming Chemoresistance in Head and Neck Squamous Cell Carcinoma: Keeping the Focus on Cancer Stem Cells, a Systematic Review

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Head and neck cancer is often resistant to chemotherapy because of cancer stem cells that survive treatment and cause recurrence. This review examined 31 studies on methods to overcome this resistance, finding that natural products like mushrooms (Ganoderma lucidum), plants (sulforaphane from broccoli, curcumin from turmeric), and synthetic compounds can enhance chemotherapy effectiveness when combined with traditional drugs. These approaches work by targeting the specific pathways that allow cancer stem cells to survive, potentially improving treatment outcomes while reducing required drug doses and side effects.

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How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?

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This comprehensive review explores how traditional healing practices from around the world use plants and mushrooms to treat cancer. The authors examine thousands of plant species and their active compounds that show promise in fighting various types of cancer through multiple mechanisms like stopping cancer cell growth and triggering cell death. The review emphasizes that proper scientific validation, standardization, and safety testing can help integrate these traditional remedies into modern cancer treatment alongside conventional chemotherapy.

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