Disease: Nail dystrophy

Onychomycosis in the US Pediatric Population—An Emphasis on Fusarium Onychomycosis

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This study examined nail fungus infections in American children using advanced molecular testing. Researchers found that elementary school-aged children (ages 6-11) have the highest rates of nail fungus, usually caused by common fungi like Trichophyton rubrum. Notably, Fusarium, an environmental fungus that was once rare in nail infections, is becoming increasingly common, especially in older teenagers, which may require different treatment approaches.

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A case of refractory onychomycosis caused by Kloeckera apiculata: Successful treatment with itraconazole

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A 32-year-old man had a stubborn fungal nail infection caused by an extremely rare yeast called Kloeckera apiculata that didn’t respond to three different antifungal treatments over several years. After being identified through specialized laboratory testing including genetic sequencing, the infection was successfully cured with a 3-month course of the oral antifungal medication itraconazole. This case is notable because it is only the fourth known case of this rare fungal infection in humans and the first one to achieve complete cure with itraconazole treatment.

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