mycotoxicosis – mycolab.ai

A comprehensive review of mycotoxins, their toxicity, and innovative detoxification methods

mycolabadmin

Mycotoxins are poisons produced by molds that commonly contaminate foods like grains, nuts, and spices, causing serious health problems in people and animals. This comprehensive review examines how these toxins affect our health, how to detect them in food, and various methods to remove or destroy them. Traditional approaches using biological agents and chemicals work well but are only partially effective, while newer innovative methods using nanoparticles and plant extracts show greater promise for more complete protection of our food supply.

The Effect of Mushroom Culture Filtrates on the Inhibition of Mycotoxins Produced by Aspergillus flavus and Aspergillus carbonarius

mycolabadmin

Researchers tested extracts from 42 different mushroom species to find ones that could prevent harmful toxins produced by mold from contaminating our food and animal feed. They discovered that two mushroom species—turkey tail mushroom and a species called Schizophyllum commune—produced compounds that blocked over 90% of toxin production. These mushroom compounds work by boosting the mold’s natural defense systems, essentially making it unable to produce the dangerous toxins.

Impact of OTAbZIP on Ochratoxin A production, mycelium growth and pathogenicity of Aspergillus westerdijkiae under water activity stress

mycolabadmin

Researchers studied how a specific gene (OTAbZIP) in a fungus called Aspergillus westerdijkiae controls the production of ochratoxin A, a poisonous substance that can contaminate food. By removing this gene, scientists found that the fungus could no longer produce the toxin, even when exposed to different moisture levels. This discovery could help prevent food contamination with this dangerous mycotoxin and protect human health.

Negative Effects of Occurrence of Mycotoxins in Animal Feed and Biological Methods of Their Detoxification: A Review

mycolabadmin

Molds that grow on grains and feed produce toxic substances called mycotoxins that can seriously harm farm animals, causing liver and kidney damage, reproductive problems, and reduced productivity. While proper storage and farming practices help prevent contamination, some mycotoxins still get through. Recent research shows that beneficial bacteria like those in yogurt and certain yeasts can effectively remove these toxins from animal feed, making it safer for livestock while protecting the environment from harmful chemicals.

Phylogeny of Aspergillus section Circumdati and inhibition of ochratoxins potential by green synthesised ZnO nanoparticles

mycolabadmin

This research studied yellow-colored fungal species that contaminate crops and can produce harmful toxins called ochratoxins. Scientists identified four different species of these fungi and found that tiny zinc oxide particles made from plant extract could reduce toxin production. The study shows promise for using these nanoparticles to protect food and agricultural products from fungal contamination.

Design of a melting curve analysis (MCA) based on multiplex real-time PCR for detection of Aspergillus terreus and Aspergillus fumigatus in cereals and oilseeds samples

mycolabadmin

This study developed a fast molecular test using real-time PCR to detect harmful Aspergillus fungi in grains and seeds. Instead of waiting 3-5 days for traditional culture methods, this new test can identify the fungi in just hours by detecting specific DNA patterns. The test was tested on 140 samples of cereals and oilseeds and proved more accurate than traditional methods, making it useful for food safety in markets and processing plants.

Phylogeny of Aspergillus section Circumdati and inhibition of ochratoxins potential by green synthesised ZnO nanoparticles

mycolabadmin

Researchers identified four species of Aspergillus fungus that contaminate crops and produce poisonous compounds called ochratoxins. They found that specially made zinc oxide nanoparticles, created using an environmentally friendly method with basil extract, can significantly reduce the amount of ochratoxins produced by these fungi. This discovery could help protect agricultural products from contamination and improve food safety.

Biocontrol of Aflatoxigenic Maize Molds Using Lactobacillus spp.-Based Formulations

mycolabadmin

This study shows that beneficial bacteria called Lactobacillus, found in traditional fermented foods like fura and gapal, can effectively reduce dangerous mold toxins (aflatoxins) in maize. Researchers tested these bacteria on contaminated maize samples and found they could reduce fungal contamination by up to 68% and completely eliminate some toxins. This natural approach offers a safer, cheaper alternative to chemical treatments while preserving food quality and safety.

Design of a melting curve analysis (MCA) based on multiplex real-time PCR for detection of Aspergillus terreus and Aspergillus fumigatus in cereals and oilseeds samples

mycolabadmin

This study developed a fast molecular test to detect harmful fungi (Aspergillus species) in grains and seeds. Traditional fungal identification takes 3-5 days, but the new PCR-based method can produce results in hours. Testing 140 grain and seed samples, the new method successfully identified two dangerous Aspergillus species that produce toxic compounds harmful to human health. This advancement helps ensure food safety by enabling quicker detection of contamination in food production facilities.

Increasing incidence of mycotoxicosis in South-Eastern Germany: a comprehensive analysis of mushroom poisonings at a University Medical Center

mycolabadmin

This study examined mushroom poisoning cases in a German hospital from 2005 to 2022 and found that poisonings have nearly doubled in recent years, likely due to more people foraging for wild mushrooms and changes in climate affecting mushroom distribution. The death cap mushroom (Amanita phalloides) caused the majority of serious cases, leading to liver and kidney failure. Researchers found that a blood-cleansing treatment called plasmapheresis could help stabilize patients with life-threatening bleeding complications while they recovered or waited for a liver transplant.

Disease: mycotoxicosis