Disease: multidrug-resistant infections

The Effect of Supplementing Mushroom Growing Substrates on the Bioactive Compounds, Antimicrobial Activity, and Antioxidant Activity of Pleurotus ostreatus

This study investigated how adding wheat bran to mushroom growing substrates affects oyster mushroom quality and medicinal properties. The researchers found that wheat bran supplementation increased mushroom yield but slightly decreased antioxidant power, while the mushrooms produced antimicrobial compounds effective against various bacteria and fungi. The mushrooms contained beneficial compounds like vitamin E and phenols, suggesting they could be developed as natural alternatives to synthetic antibiotics.

Read More »

Caged-hypocrellin mediated photodynamic therapy induces chromatin remodeling and disrupts mitochondrial energy metabolism in multidrug-resistant Candida auris

Researchers developed a new photodynamic therapy treatment using a light-activated compound called COP1T-HA to fight drug-resistant Candida auris infections. The therapy works by reorganizing the fungal cell’s genetic material architecture and disrupting energy production in mitochondria, ultimately killing the fungal cells. This approach represents a novel strategy to overcome antibiotic resistance, as it targets multiple cellular processes rather than a single pathway that fungi can easily resist.

Read More »
Scroll to Top