Disease: mental illness

Overcoming Solubility Challenges: Micronization of Berberine Using the GAS Antisolvent Technique

Berberine is a traditional medicinal compound that could treat many diseases but doesn’t work well in the body because it doesn’t dissolve in water. Researchers used a special technique with pressurized carbon dioxide to break berberine into much smaller particles. This made the particles dissolve 18% better in water, which could make berberine-based medicines more effective at treating diabetes, high cholesterol, and other conditions.

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Reporting of psychotherapeutic methods in psychedelic treatments: on the road to ethical, professional and regulatory oversight

Researchers reviewed 45 studies on how psychedelic drugs like psilocybin, MDMA, and LSD are used to treat mental health conditions. They found that scientists were not describing the psychological counseling that accompanies these treatments in a consistent or detailed way, making it hard to understand how treatments really work. The study calls for better documentation standards so that treatments can be properly regulated, replicated, and made safer for patients.

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Psychedelic Mushrooms in the USA: Knowledge, Patterns of Use, and Association With Health Outcomes

This study surveyed over 250 million representative American adults about their use of psychedelic mushrooms. Researchers found that about 1.7% of US adults used psychedelic mushrooms in the past year, primarily for general mental health and well-being. Interestingly, those who used them reported higher levels of depression and anxiety, suggesting people with mental health challenges may be self-treating with mushrooms. The findings highlight the need for evidence-based guidelines as more Americans explore psychedelics for health purposes.

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Universal Platform Based on Carbon Nanotubes Functionalised with Carboxylic Acid Groups for Multi-Analyte Enzymatic Biosensing

Scientists have created a tiny biosensor platform using carbon nanotubes that can detect multiple important molecules in blood and food simultaneously. The sensor uses special enzymes that recognize glucose, lactate, glutamate, and dopamine, making it useful for monitoring diabetes, fatigue levels, and brain chemistry. By adding another enzyme called catalase, the sensor works even better and across a wider range of concentrations. Tests on real blood and food samples show the sensor accurately measures these important biomarkers, making it potentially valuable for both health monitoring and food quality testing.

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