Disease: Liver cancer

Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

This review examines how traditional Chinese medicine ingredients can boost the body’s natural ability to fight cancer when combined with tiny nanoparticles that deliver drugs more effectively. The nanoparticles help TCM compounds work better by improving how they dissolve, how long they stay in the body, and where they target. By activating immune cells like natural killer cells and dendritic cells while reducing immune-suppressing cells, this combination approach offers a promising new strategy for cancer treatment with fewer side effects.

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Functional Components from the Liquid Fermentation of Edible and Medicinal Fungi and Their Food Applications in China

Mushroom mycelium grown in liquid fermentation produces many beneficial compounds like polysaccharides and proteins that support immune function and may help fight cancer and oxidative stress. These fermented mushroom products can be added to foods, beverages, and health supplements to boost their nutritional value and health benefits. Studies show that fermented mushroom mycelium sometimes contains higher levels of beneficial compounds compared to whole mushroom fruiting bodies, making it a promising ingredient for functional foods and health products.

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The Potential of Mushroom Extracts to Improve Chemotherapy Efficacy in Cancer Cells: A Systematic Review

This systematic review examines how mushroom extracts can make chemotherapy more effective at treating cancer, particularly by helping overcome cancer cells’ resistance to drugs. Researchers found that various mushroom species contain compounds that work together with chemotherapy drugs to kill cancer cells more effectively through different cellular mechanisms. The results suggest mushroom extracts could be a promising natural complement to conventional cancer treatments, though more research is needed before they can be used clinically.

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Therapeutic Effects of Natural Products on Liver Cancer and Their Potential Mechanisms

This review examines how natural products from plants, fungi, and marine organisms can help treat liver cancer more safely and effectively than current drugs. These natural compounds work through multiple pathways such as triggering cancer cell death, stopping cell growth, and boosting the immune system. The research found that seven categories of natural products show promise, with sources ranging from ginseng and turmeric to mushrooms and seaweed, offering potential new treatment options that could reduce side effects and drug resistance.

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Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

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In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

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A Review of Research Progress on the Microbial or Enzymatic Degradation and Mechanism of Aflatoxin B1

Aflatoxin B1 is a dangerous toxin found in contaminated cereals and food products that can cause serious diseases including liver cancer. Scientists have discovered that certain bacteria and fungi can naturally break down this toxin into less harmful substances through their enzymes. This review summarizes different microorganisms and enzymes that can degrade aflatoxin B1, explaining how they work and what safe products they create, offering hope for safer food storage and treatment.

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The Efficacy of Clove Oil Against Aspergillus flavus and the Production of Aflatoxin B1 in Organic Peanuts in Georgia

Researchers tested clove essential oil as a natural antifungal treatment for peanuts infected with a mold that produces aflatoxin, a dangerous toxin harmful to human health. They found that clove oil significantly reduced both the mold growth and toxin production, with the best results at moderate concentrations. This discovery offers organic farmers an eco-friendly alternative to synthetic fungicides for protecting their peanut crops. The findings could help reduce a major agricultural problem that costs the Southeast millions of dollars annually.

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Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications

Melanin from edible mushrooms like black wood ear and reishi offers a natural, sustainable alternative to synthetic melanins with impressive health benefits. These mushroom melanins demonstrate powerful antioxidant and antibacterial properties, protect against radiation damage, and can help maintain liver health. New extraction methods using special solvents are making it easier to obtain pure melanin from mushrooms efficiently, opening doors for its use in food, cosmetics, and medicines.

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Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

Cordyceps militaris is a medicinal fungus used in traditional medicine to treat fatigue, boost immunity, and fight disease. This comprehensive review explains how different growing conditions—including the type of food (substrate), light exposure, temperature, and nutrient ratios—affect the production of powerful healing compounds like cordycepin and polysaccharides. The review compares growing methods using grains versus insects, showing that insect-based cultivation produces higher concentrations of beneficial compounds. Key recommendations for the future include developing standardized growing protocols and integrating advanced research techniques to scale up production sustainably.

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