Disease: Leukemia

Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer

Ganoderma lucidum, a mushroom used in traditional medicine for thousands of years, shows promise in fighting certain blood cancers like leukemia and lymphoma. The mushroom contains special compounds that can kill cancer cells in multiple ways—by triggering cancer cell death, boosting the immune system, and preventing cancer cell growth. While laboratory studies are very encouraging, more testing in humans is needed before it can be used as a standard cancer treatment.

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The Transformation and Protein Expression of the Edible Mushroom Stropharia rugosoannulata Protoplasts by Agrobacterium-tumefaciens-Mediated Transformation

Scientists developed a genetic engineering technique to modify king stropharia (a cultivated edible mushroom) by inserting foreign genes into its cells. This breakthrough allows researchers to study how the mushroom grows and produces beneficial compounds. The technique uses a bacterium called Agrobacterium tumefaciens to naturally deliver genes into mushroom cells, similar to how it infects plants. This advancement could lead to improved cultivation practices and enhanced nutritional or medicinal properties.

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Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

This review examines how traditional Chinese medicine ingredients can boost the body’s natural ability to fight cancer when combined with tiny nanoparticles that deliver drugs more effectively. The nanoparticles help TCM compounds work better by improving how they dissolve, how long they stay in the body, and where they target. By activating immune cells like natural killer cells and dendritic cells while reducing immune-suppressing cells, this combination approach offers a promising new strategy for cancer treatment with fewer side effects.

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The Anticancer Potential of Edible Mushrooms: A Review of Selected Species from Roztocze, Poland

This review examines edible mushrooms found in Poland’s Roztocze region for their potential to fight cancer. These mushrooms contain natural compounds like polysaccharides and proteins that can kill cancer cells in laboratory studies through various mechanisms, including triggering cell death and boosting immune function. While promising, these findings from laboratory and animal studies need further development before becoming clinical treatments.

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Domestication of a magic therapeutical wine glass fungus (Podoscypha petalodes) from Pakistan

Researchers successfully grew Podoscypha petalodes, a medicinal mushroom known as wine glass fungus, under controlled conditions for the first time. The best growth was achieved using a mixture of sawdust and tea waste at 28°C, which produced high yields in just 10 days. This breakthrough means that this therapeutic fungus, which has antiviral and anti-cancer properties, can now be cultivated year-round commercially instead of relying on rare wild specimens.

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Ganoderma lucidum methanolic extract as a potent phytoconstituent: characterization, in-vitro antimicrobial and cytotoxic activity

Researchers tested a medicinal mushroom extract (Reishi/Ganoderma lucidum) to see if it could fight cancer and bacterial infections. The extract showed promising results, being particularly effective against blood cancer and breast cancer cells while being less toxic to normal healthy cells. It also killed bacteria better than some standard antibiotics, suggesting it could potentially be developed into a new type of medicine for treating cancer and infections.

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Chaga mushroom triterpenoids as adjuncts to minimally invasive cancer therapies: A review

Chaga mushroom, a fungus that grows on birch trees, contains special compounds called triterpenoids that can kill cancer cells in laboratory tests. Some of these compounds, particularly inotodiol and betulinic acid, show anti-cancer activity similar to or better than conventional chemotherapy drugs. While promising, researchers need to improve how these compounds are absorbed in the body and test them more thoroughly in animals and humans before they can be used clinically.

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Fruit-Based Fermented Beverages: Contamination Sources and Emerging Technologies Applied to Assure Their Safety

This review examines safety concerns in popular fermented fruit drinks like wine and cider. It identifies major contamination risks including toxic compounds produced by molds (mycotoxins), harmful byproducts from fermentation (biogenic amines), pesticide residues, heavy metals, and plastic particles. The authors recommend combining traditional safety practices with modern technologies like electric fields and high-pressure treatments to ensure these beverages remain safe to drink while maintaining their health benefits.

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The Emerging Role of Oyster Mushrooms as a Functional Food for Complementary Cancer Therapy

Oyster mushrooms contain special compounds that may help fight cancer and boost the immune system. These mushrooms have antioxidants and other natural chemicals that can slow cancer cell growth and trigger cancer cells to die. When combined with standard cancer treatments, oyster mushroom supplements might improve quality of life and reduce side effects. More research is needed, but oyster mushrooms show promise as an affordable, natural addition to cancer treatment plans.

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Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

Mushrooms are nutritional powerhouses packed with proteins, vitamins, minerals, and special compounds that fight disease. They can help prevent and manage serious conditions like cancer, heart disease, and diabetes while supporting overall health and immunity. Beyond the kitchen, mushrooms are being developed into medicines and cosmetic products. Growing and using mushrooms also helps the environment by creating sustainable alternatives to traditional medicines and animal feeds.

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