Disease: keratomycosis

The impact of climate change on the epidemiology of fungal infections: implications for diagnosis, treatment, and public health strategies

Climate change is making it easier for dangerous fungi to grow and spread to new areas where people have never encountered them before. As temperatures rise and weather becomes more extreme, fungi are becoming resistant to our medicines, especially antifungal drugs used in both farming and hospitals. People living in poverty, displaced by natural disasters, and those without good healthcare access are most vulnerable to these infections. We need to act quickly by developing new treatments, improving diagnosis, reducing agricultural fungicide use, and strengthening healthcare systems in vulnerable communities.

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Candida tropicalis Fungal Keratitis: A Case Report and Literature Review

A 66-year-old patient with a long history of corneal problems developed a serious eye infection caused by a fungus called Candida tropicalis. Doctors identified the infection through laboratory tests and treated it successfully with antifungal medications. This is the first documented case of this particular fungal infection in Morocco and highlights the importance of testing for fungal infections in patients with existing eye problems.

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Taxonomic revision of Bisifusarium (Nectriaceae)

Scientists have identified and formally named 8 new species of Bisifusarium, a genus of fungi found in cheese, soil, and some human infections. Using genetic analysis and careful observation of fungal structures, researchers studied 116 fungal samples collected from around the world. This work more than doubled the known number of Bisifusarium species from 16 to over 24, providing clearer identification methods for future research in food science and medicine.

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Fusarium Corneal Abscess: A Case Report

A healthy 20-year-old man developed a serious fungal eye infection caused by Fusarium, a soil fungus, despite having no typical risk factors like eye injury or contact lens wear. Doctors diagnosed the infection through laboratory tests showing fungal filaments and growing the organism in culture. The patient required multiple treatments including antifungal eye drops, injections directly into the cornea, and a graft from amniotic membrane (placenta tissue) to save his vision. The case demonstrates that fungal eye infections can occasionally occur in completely healthy people without obvious causes.

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Favorable outcome of Lasiodiplodia theobromae keratomycosis: a clinical case and systematic review

A 74-year-old farmer developed a serious fungal eye infection caused by Lasiodiplodia theobromae, a rare tropical fungus. Instead of requiring eye surgery, the patient was successfully treated with a combination of two antifungal medications applied as eye drops and taken orally for eight weeks. This case is significant because it’s the first documented successful medical treatment of this particular fungal infection, highlighting the importance of quick diagnosis and avoiding corticosteroid eye drops that can worsen fungal infections.

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Taxonomic revision of Bisifusarium (Nectriaceae)

This study provides a comprehensive update on Bisifusarium fungi, a group that includes species used in cheese production and some that can cause human infections. Researchers examined 116 fungal isolates from around the world and identified 25 distinct lineages using DNA analysis. They formally described 8 new species and provided detailed descriptions and photos of previously poorly documented species. This work doubles the known diversity of this fungal genus and will help scientists and medical professionals better identify and understand these fungi.

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