Disease: keratitis

Isolation and identification of Fusarium species from the water systems of ICUs and transplant wards of hospitals and determination of the in vitro susceptibilities of isolates to conventional antifungals

Researchers found dangerous Fusarium fungal species in water systems of hospital ICU wards in Tehran, Iran. These fungi can spread through water fixtures and pose serious risks to patients with weak immune systems. Testing showed that certain antifungal drugs like posaconazole and voriconazole worked well against these fungi, but other drugs were less effective. The study emphasizes the importance of better water management and safety measures in hospitals to protect vulnerable patients.

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Insights into Persian Gulf Beach Sand Mycobiomes: Promises and Challenges in Fungal Diversity

Researchers studied fungi living in sand and water along Persian Gulf beaches to understand potential health risks for swimmers. They found that fungal species, particularly Aspergillus terreus, were abundant in beach sand, with some fungi showing resistance to common antifungal medicines. The study suggests beaches need better monitoring and sanitation practices to protect public health, especially during busy bathing seasons when many visitors enjoy the coast.

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Insights into Persian Gulf Beach Sand Mycobiomes: Promises and Challenges in Fungal Diversity

Researchers studied fungi in beach sand and water along the Persian Gulf and Sea of Oman coasts during summer months. They found high levels of potentially harmful fungi, especially Aspergillus terreus, which can cause serious respiratory infections. Many of these fungi showed resistance to common antifungal medications. The study recommends better hygiene awareness for beach visitors and establishing safety standards for these popular recreational areas.

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Endogenous Endophthalmitis: An underestimated serious complication in patients with disseminated fusariosis

An 18-year-old boy with acute leukemia developed a serious fungal infection caused by Fusarium mold that spread throughout his body, including to both eyes. Despite receiving intensive antifungal medications injected directly into his eyes along with systemic treatment, he lost his vision. However, through aggressive combined therapy, doctors were able to save both eyes and continue his cancer treatment successfully.

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Insights into Persian Gulf Beach Sand Mycobiomes: Promises and Challenges in Fungal Diversity

Researchers studied fungi found in sand and water at beaches along Iran’s Persian Gulf and Sea of Oman coastlines. They discovered high levels of potentially harmful fungi, particularly Aspergillus terreus, which can cause respiratory infections. The study found that while some antifungal drugs like voriconazole were effective, some fungi showed resistance to common treatments. This information is important for protecting swimmers and beach visitors from fungal health risks.

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Things you wanted to know about fungal extracellular vesicles (but were afraid to ask)

Fungal extracellular vesicles are tiny particles released by fungal cells that play important roles in how fungi cause disease and how our immune system responds. These particles can either help fight infections or make them worse depending on the type of fungus and conditions involved. Scientists are discovering that these vesicles could potentially be used as vaccines and may explain why some antifungal drugs stop working.

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Insights into Persian Gulf Beach Sand Mycobiomes: Promises and Challenges in Fungal Diversity

Researchers studied fungi living in beach sand and seawater along Iran’s Persian Gulf and Sea of Oman coastlines to understand potential health risks. They found that dangerous fungi, particularly Aspergillus species, were present at levels exceeding safe thresholds for swimmers and beach visitors. Many of these fungi showed resistance to common antifungal medications, which is concerning for people with weakened immune systems. The study suggests that beaches need better monitoring and sanitation programs to protect public health.

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The frequency distribution of Aspergillus section Nigri from clinical and environmental samples in Iran

Researchers studied black mold species (Aspergillus section Nigri) found in hospitals and the environment across Iran. They identified eight different species and found that certain types like A. welwitschiae were more common in ear infections while A. tubingensis was more prevalent in soil and air. These findings are important because some of these molds cause serious infections in humans and understanding where they live helps doctors predict and treat infections.

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Olorofim activity against multidrug-resistant Fusarium unveils intra-species and inter-species variability

Researchers tested a new antifungal drug called olorofim against 253 different Fusarium fungi that infect humans. Fusarium is particularly dangerous for people with weakened immune systems and resists most common antifungals. The study found that olorofim works, but its effectiveness varies significantly depending on which type of Fusarium is present. While these lab results are promising, additional testing in animal models is needed before it can be used clinically.

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