Disease: Irritable bowel syndrome

How Do Cyclodextrins and Dextrans Affect the Gut Microbiome? Review of Prebiotic Activity

Cyclodextrins and dextrans are substances commonly used in medicines that may have unexpected health benefits for your gut bacteria. Research shows these compounds can help beneficial bacteria like Lactobacillus and Bifidobacterium grow better in your digestive system. When these good bacteria ferment these substances, they produce helpful compounds called short-chain fatty acids that improve overall gut health and may help with conditions like obesity and inflammation.

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Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT)

Researchers studied a kombucha tea drink enriched with fiber from chicory root in healthy adults over six weeks. The study found that people who consumed the fiber-enriched kombucha had lower triglyceride levels (blood fats) and beneficial changes in their gut bacteria, particularly an increase in Bifidobacterium, a bacteria known to support digestive health. These results suggest that this type of kombucha could be beneficial for metabolic and gut health, though more research is needed to confirm these benefits.

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Galacto-Oligosaccharides Exert Bifidogenic Effects at Capsule-Compatible Ultra-Low Doses

This study tested whether tiny doses of a prebiotic called galacto-oligosaccharides (GOS) could be effective when taken in capsule form instead of large sachets. Researchers used a specially designed laboratory system to simulate how these compounds work in the human gut. Even at the lowest dose tested (0.5 g), the GOS successfully increased beneficial gut bacteria and produced helpful compounds that support digestive health, while producing minimal gas.

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Sea buckthorn bioactive metabolites and their pharmacological potential in digestive diseases

Sea buckthorn is an ancient medicinal plant containing hundreds of bioactive compounds that show promise in treating digestive diseases like stomach ulcers, colitis, and liver problems. This comprehensive review of 85 scientific studies found that sea buckthorn’s active ingredients work through multiple mechanisms including reducing inflammation, fighting harmful bacteria, protecting the intestinal lining, and balancing gut bacteria. The research suggests sea buckthorn could become a valuable natural supplement for digestive health, though more clinical trials are needed to confirm optimal doses and long-term effectiveness in humans.

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A comprehensive overview of the effects of probiotics, prebiotics and synbiotics on the gut-brain axis

This comprehensive review examines how probiotics (beneficial live bacteria), prebiotics (food for beneficial bacteria), and synbiotics (combinations of both) can influence communication between the gut and brain. These interventions can produce beneficial compounds like GABA and serotonin, strengthen the gut barrier, and reduce inflammation, potentially helping with mood, anxiety, cognition, and various digestive disorders. However, effects vary greatly depending on the specific strain used, dosage, and individual differences in gut bacteria, and more large-scale studies are needed to confirm long-term clinical benefits.

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Nanoencapsulation of Biotics: Feasibility to Enhance Stability and Delivery for Improved Gut Health

This review explores how tiny nanoparticles can protect beneficial bacteria and dietary compounds as they travel through the digestive system. These nanotechnologies help probiotics survive stomach acid and reach the intestines where they provide health benefits. The research shows promising results for treating digestive diseases and improving overall gut health through better delivery of microbiota-modulating substances.

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Study protocol for ‘Psilocybin in patients with fibromyalgia: brain biomarkers of action’

Researchers are testing whether psilocybin (the active compound in magic mushrooms) combined with therapeutic support can help people with fibromyalgia, a chronic pain condition. The study will measure brain activity using EEG and brain imaging to understand how psilocybin might reduce pain and improve mental health. Twenty patients will receive guided psilocybin sessions over eight weeks while researchers track changes in brain function and pain levels.

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Amorphophallus konjac: traditional uses, bioactive potential, and emerging health applications

Konjac is a plant used in Asian cuisine and traditional medicine for thousands of years that contains a special fiber called glucomannan. This fiber can help with weight loss, blood sugar control, and cholesterol reduction while also supporting a healthy gut and reducing inflammation. Modern research shows promising potential for using konjac to help prevent serious diseases like colorectal cancer and manage conditions like diabetes and inflammatory bowel disease.

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Synbiotic yogurt with nanoparticle entrapped rice straw hemicellulose for immediate probiotic support and prebiotic delivery

Scientists created a new type of yogurt that contains beneficial bacteria and special prebiotics from rice straw. The innovation uses tiny nanoparticles to protect some of the prebiotics so they reach your gut intact, while free prebiotics immediately feed the beneficial bacteria in the yogurt during storage. This dual-delivery approach keeps the yogurt fresher longer while ensuring you get maximum health benefits for your digestive system.

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