Disease: intra-abdominal candidiasis

Reevaluating the Value of (1,3)-β-D-Glucan for the Diagnosis of Intra-Abdominal Candidiasis in Critically Ill Patients: Current Evidence and Future Directions

This review examines how a fungal biomarker called beta-D-glucan (BDG) can help doctors diagnose yeast infections in the abdomens of critically ill patients. While BDG tests in the blood are available, they give many false positives. Testing BDG directly in fluid from the abdomen appears more accurate, especially when combined with blood tests. However, more research is needed before hospitals widely adopt this approach in daily practice.

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Invasive Candidiasis in Contexts of Armed Conflict, High Violence, and Forced Displacement in Latin America and the Caribbean (2005–2025)

Invasive candidiasis, a serious fungal blood infection caused by Candida species, is a major health crisis in Latin America and the Caribbean with death rates reaching 60% in vulnerable populations. The disease is worsening in areas affected by armed conflict, violence, and displacement where poor living conditions, overcrowding, malnutrition, and lack of healthcare create ideal conditions for the infection to develop and spread. Antifungal drugs are often unavailable or too expensive, and drug-resistant strains of Candida are becoming increasingly common, making treatment extremely challenging in these regions.

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Invasive Candidiasis in Contexts of Armed Conflict, High Violence, and Forced Displacement in Latin America and the Caribbean (2005–2025)

This comprehensive review examines candida fungal infections in conflict-affected areas of Latin America and the Caribbean, where wars, violence, and displacement create dangerous conditions that make infections more likely and harder to treat. In these regions, mortality from candida bloodstream infections reaches 65% or higher among displaced populations, compared to about 45-60% in regular hospitals. The main problems are lack of proper diagnostic equipment, limited access to effective antifungal medications, malnutrition, overcrowding in shelters, and the emergence of drug-resistant fungal strains.

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