Disease: infertility

Targeting Polycystic Ovary Syndrome (PCOS) Pathophysiology with Flavonoids: From Adipokine–Cytokine Crosstalk to Insulin Resistance and Reproductive Dysfunctions

Polycystic ovary syndrome (PCOS) is a common hormonal disorder affecting millions of women that causes irregular periods, infertility, and metabolic problems. Flavonoids are beneficial plant compounds found in fruits, vegetables, and tea that show promise in treating PCOS by improving insulin sensitivity, reducing inflammation, and balancing hormones. While current medications have limited benefits and side effects, flavonoid supplements could offer a safer, natural way to address multiple PCOS problems simultaneously. However, more large-scale clinical studies are needed to confirm their effectiveness and establish optimal dosing.

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Yamabushitake Mushroom (Hericium erinaceus (Bull.) Pers. 1797) Mycelium Improves Reproductive System Dysfunction in Male Rats Induced by Polystyrene Microplastics

A study found that Yamabushitake mushroom extract can help protect male reproductive health from damage caused by polystyrene microplastics found in everyday plastic products. The mushroom’s active compound, erinacine A, reduced inflammation and oxidative stress in rats, improved hormone levels, and enhanced sperm quality. This research suggests the mushroom could be developed into a supplement for men concerned about their fertility and reproductive health in our plastic-filled environment.

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