immunodeficiency – mycolab.ai

Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

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Mushrooms are nutritious foods that contain beneficial compounds like β-glucans and polysaccharides which can help wounds heal faster. These compounds work by activating immune cells and promoting collagen production, which are essential for skin repair. Research shows that mushroom extracts from species like Ganoderma lucidum and Hericium erinaceus can accelerate wound closure in experimental models and may benefit diabetic wound care and burn treatment.

Enhancing Environmental and Human Health Management Through the Integration of Advanced Revitalization Technologies Utilizing Artificial Intelligence

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This paper describes how combining artificial intelligence with environmental monitoring can help us better understand how pollution harms our health. The authors propose a seven-step system that collects data on pollution levels in air, water, and soil alongside health information from communities. By using AI to analyze these massive datasets together, scientists and doctors can more quickly identify which pollutants are causing specific health problems and design better treatments for affected people and environments.

Mitochondrial genome characterization, evolution and intron dynamics of the entomopathogenic genus Cordyceps

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This research examined the genetic instruction manuals (mitochondrial DNA) of seven different Cordyceps fungal species. Scientists found that these fungi have varying amounts of genetic material, primarily due to differences in introns—sections that can be inserted or removed from genes. By comparing their genomes, researchers clarified how different Cordyceps species are related to each other evolutionarily, providing better tools for identifying and classifying these medically valuable fungi.

Cultivation and mycelium production from spore suspensions of desert truffles: prospective use as inoculum for host plants in arid zones

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Desert truffles are valuable edible fungi that grow in arid regions and have health benefits. This research successfully grew two desert truffle species (Terfezia boudieri and Tirmania nivea) in laboratory conditions using standard culture media. The study found that potato dextrose agar was the best medium for rapid growth, while both media supported good mycelial development. This breakthrough could enable large-scale production of truffle inoculum for reforestation programs in Morocco’s degraded desert areas.

Non-Targeted Metabolomics Analysis Reveals Metabolite Profiles Change During Whey Fermentation with Kluyveromyces marxianus

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Scientists fermented whey (a dairy byproduct) using a special yeast called Kluyveromyces marxianus to create a nutrient-rich food. Using advanced analysis, they found that fermentation breaks down large proteins and fats into smaller, more beneficial compounds including amino acids and omega-3 fatty acids. The fermented whey showed significant increases in health-promoting substances that could help reduce inflammation, prevent disease, and improve overall nutrition.

Data analysis of patients with positive mould or dimorphic fungal cultures from sterile sites

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This study examined 48 patients with serious mould and fungal infections at a South African hospital between 2014-2017. Most infections occurred in people with weak immune systems, especially those with HIV. The most common fungal type was Aspergillus. Even with appropriate antifungal medicines, one-quarter of patients died, highlighting how serious these infections can be.

Mixing oak and eucalyptus sawdusts improves shiitake (Lentinula edodes) yield and nutritional value

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This research explores growing shiitake mushrooms on different wood sawdust mixtures available in Lebanon. A combination of eucalyptus and oak sawdust outperformed oak alone, producing more mushrooms with better nutritional content including higher protein and fiber. This discovery helps local farmers improve mushroom production using readily available materials while creating healthier, more nutritious food.

Polymerase Chain Reaction on Respiratory Tract Specimens of Immunocompromised Patients to Diagnose Pneumocystis Pneumonia: A Systematic Review and Meta-analysis

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This study analyzed how well PCR tests detect Pneumocystis pneumonia, a serious fungal lung infection in immunocompromised patients. The research reviewed 55 studies with over 11,000 tests and found that PCR testing of fluid from the lungs or induced sputum works very well, especially at ruling out the disease when negative. However, positive test results need careful interpretation because the test can detect the fungus even when it’s just colonizing rather than causing active infection.

Recent Discoveries on Marine Organism Immunomodulatory Activities

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Scientists are discovering that creatures from the ocean produce powerful substances that can help our immune system fight diseases like cancer and inflammation. These marine organisms—from tiny algae to sponges to fish—create natural compounds that can either boost or calm down our immune response depending on what we need. Several of these ocean-derived medicines are already approved for treating serious diseases, and many more are being tested in clinical trials. The ocean covers 70% of our planet and most of it remains unexplored, suggesting there are many more beneficial compounds waiting to be discovered.

Maintaining the Quality and Nutritional Integrity of Chilled Cordyceps sinensis: Comparative Effects and Mechanisms of Modified Atmosphere Packaging and UV-Based Interventions

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Cordyceps sinensis is a highly valued medicinal mushroom that loses its nutritional benefits quickly when stored fresh. This research tested different storage methods to keep it fresh longer, finding that packaging in a special gas mixture (80% nitrogen and 20% carbon dioxide) worked best for preserving its valuable compounds during 12 days of cold storage. The study also found that using UV light treatment could reduce browning, while vacuum sealing best prevented the mushroom from drying out.

Disease: immunodeficiency