Disease: hypertension

Comparative transcriptome analysis reveals the genetic basis underlying the biosynthesis of polysaccharides in Hericium erinaceus

Researchers studied six different strains of lion’s mane mushrooms to understand how they produce beneficial compounds called polysaccharides. Using advanced genetic analysis, they identified thirteen key genes responsible for making these health-promoting molecules. The study found that a strain called PZH-05 produced the most polysaccharides, and its genes were more active than in other strains. This research helps explain why lion’s mane mushrooms are effective for boosting immunity, fighting cancer, and managing blood sugar.

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Acute fungal endometritis in women with abnormal uterine bleeding: Clinical and microbiological insights

This study examined a rare fungal infection of the uterus called fungal endometritis that causes abnormal bleeding and discomfort in women. Researchers found that about 12% of women with unexplained abnormal bleeding had this fungal infection, which was caused by different species of Candida yeast. A simple test using vaginal swabs was not effective for diagnosis; instead, doctors needed to take samples directly from the uterine lining. Treatment with an antifungal medication called voriconazole combined with surgical cleaning was successful in all cases studied.

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Invasive Fusarium rhinosinusitis in COVID-19 patients: report of three cases with successful management

This study reports three cases of rare fungal sinus infections caused by Fusarium species that developed in COVID-19 patients. All three patients were successfully treated with a combination of surgical removal of infected tissue and antifungal medications. The cases highlight how COVID-19 and the use of steroids to treat it can increase the risk of serious fungal infections, emphasizing the importance of early detection and prompt treatment.

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A Rare Case of Methyldopa-Induced Hepatitis

A 31-year-old woman developed severe liver inflammation (hepatitis) six weeks after starting methyldopa, a common blood pressure medication. After stopping the drug, her liver function returned to normal without needing steroids or other intensive treatments. This case reminds doctors that even commonly used, safe medications can rarely cause serious liver problems and should be considered when patients develop unexplained liver inflammation.

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Purification, Structural Characteristics, Bioactive Properties, and Applications of Naematelia aurantialba Polysaccharides: A Comprehensive Review

Golden ear (Naematelia aurantialba) is a traditional Chinese medicinal mushroom recently approved as a cosmetic ingredient. This comprehensive review examines how scientists extract and purify beneficial compounds called polysaccharides from this fungus, which can help manage blood sugar, boost immunity, reduce inflammation, and protect against oxidative damage. The mushroom shows promise as a natural ingredient for foods, supplements, and skincare products with potential health benefits.

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Transcriptome Analysis Reveals Critical Genes Involved in the Response of Stropharia rugosoannulata to High Temperature and Drought Stress

This study examined how a type of edible mushroom called Stropharia rugosoannulata responds to high heat and dry conditions by analyzing which genes become active. Researchers found that under stress, the mushroom activates specific genes that help it survive, particularly through a cellular communication pathway called MAPK. They identified 15 key genes that could be useful for breeding mushroom varieties that better withstand harsh growing conditions, which could improve mushroom farming efficiency.

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Purification, Structural Characteristics, Bioactive Properties, and Applications of Naematelia aurantialba Polysaccharides: A Comprehensive Review

Golden ear (Naematelia aurantialba) is a traditional Chinese fungus that is becoming increasingly popular for its health benefits. This comprehensive review explains how scientists extract and purify the beneficial polysaccharides from golden ear, and what makes them effective against diseases like diabetes and inflammation. The research shows these mushroom polysaccharides could be used in medicines, functional foods, and even cosmetics to improve human health.

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Mycobiome of Stool, Blood, Thrombus and Vessel Wall in Abdominal Aortic Aneurysm Patients

This study examined fungal communities in blood, stool, and damaged aorta tissues from patients with abdominal aortic aneurysm, a serious condition where the main blood vessel weakens and bulges. Researchers found that healthy blood vessels contain protective fungi called Tomentella, while damaged vessels have high levels of harmful fungi called Malassezia. Interestingly, the fungi found in damaged vessel walls may not come directly from the gut, suggesting they originate from other body parts like the mouth or skin. These findings suggest that controlling fungal communities with targeted antifungal treatments might help prevent or slow aneurysm development.

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Promoting rational herb-drug use through pharmacy-led advice and home visits in NCD patients

This study showed that when pharmacists visited NCD patients at home and provided education about the risks of combining herbal products with prescribed medications, patients significantly improved their knowledge and safe usage behaviors. The intervention successfully reduced the number of patients at risk of harmful herb-drug interactions from 37.5% to 25%. The findings suggest that simple home-based pharmacist counseling can be an effective way to help chronic disease patients safely use both herbs and medications together.

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