Disease: hypersensitivity pneumonitis

Diversity and functions of fungal VOCs with special reference to the multiple bioactivities of the mushroom alcohol

Fungi release various volatile compounds (VOCs) that have different effects on organisms and the environment. The most notable fungal VOC is 1-octen-3-ol, also called mushroom alcohol, which gives mushrooms their distinctive smell. This compound can inhibit fungal growth, repel insects, and help control plant diseases, but at high concentrations it may be toxic to humans and trigger immune responses. Scientists use fruit flies as a model to study how these fungal compounds affect health.

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Performance of the VITEK® MS system for the identification of filamentous fungi in a microbiological laboratory in Chile

Researchers tested a fast machine called VITEK® MS for identifying dangerous mold infections in patients. The machine correctly identified over 91% of fungal samples, which is much better than waiting weeks for traditional laboratory methods. This technology could help doctors start treatment much faster for patients with serious mold infections, potentially saving lives.

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Stonebrood Disease—Histomorphological Changes in Honey Bee Larvae (Apis mellifera) Experimentally Infected with Aspergillus flavus

Stonebrood is a rare fungal disease of honey bees caused by Aspergillus flavus that can kill bee larvae very quickly. Researchers experimentally infected bee larvae with the fungus and tracked how the disease progressed, finding that larvae died within 48 hours of infection. The study revealed that the fungus likely kills bees by producing toxins rather than by physical damage, and poses a health risk to beekeepers who inhale the fungal spores.

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Performance of the VITEK® MS system for the identification of filamentous fungi in a microbiological laboratory in Chile

This study tested a new laboratory technology called VITEK® MS for quickly identifying mold infections in patients. Researchers tested the system on 67 mold samples representing 35 different species. The technology successfully identified over 91% of the mold samples accurately without any misidentifications, making it a reliable tool for hospitals to quickly determine what type of mold is causing an infection so doctors can prescribe the right antifungal medication.

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Microfungus Podosphaera fusca and the Fungus-like Organism Peronospora ficariae as Potential Inhalant Allergens in a Mouse Model of Asthma

This study investigated whether two plant parasites that cause powdery and downy mildew could trigger asthma-like reactions in mice. Researchers found that extracts from these fungi induced immune responses similar to those caused by known allergens like ovalbumin, though somewhat weaker. The results suggest these organisms should be recognized as potential sources of respiratory allergies in humans. This finding may help explain some cases of allergies where the specific cause has been difficult to identify.

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Microfungus Podosphaera fusca and the Fungus-like Organism Peronospora ficariae as Potential Inhalant Allergens in a Mouse Model of Asthma

Researchers studied two types of plant fungi that infect common vegetables and plants to determine if they could cause asthma in mice. They found that both organisms triggered immune responses similar to those caused by known allergens, producing inflammation and asthma-like symptoms. Although their effects were weaker than the reference allergen ovalbumin, both fungi showed significant potential as respiratory allergens. This research suggests these plant parasites should be recognized as possible triggers for asthma and allergic reactions in people.

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The influence of car traffic on airborne fungal diversity in Tianjin, China

This study examined how car traffic affects fungal spores in the air in Tianjin, China. Researchers found that during rush hours when traffic was heaviest, there were more fungal spores in the air, particularly species that cause allergies and respiratory problems like asthma. The findings suggest that reducing car traffic could help improve air quality and reduce health risks from airborne fungal exposure in cities.

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Stonebrood Disease—Histomorphological Changes in Honey Bee Larvae (Apis mellifera) Experimentally Infected with Aspergillus flavus

Researchers studied how a rare fungal disease called stonebrood affects honey bee larvae by infecting them with the fungus Aspergillus flavus. They found that the fungus establishes in the bee’s gut within 24 hours and kills the larvae within two days, likely through production of toxic compounds. The study reveals three stages of infection progression and highlights why beekeepers need protection when handling infected colonies.

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Usefulness of combining computed tomography and air sac fluid examination to rule out aspergillosis: case study in two gentoo penguins (Pygoscelis papua) with respiratory clinical signs

Two penguins at an aquarium showed respiratory problems and were suspected of having a serious fungal infection called aspergillosis. Doctors used CT scans to identify fluid in their air sacs and collected samples for testing. The tests showed the penguins did not have the fungal infection, so they did not need antifungal medications. Both penguins recovered naturally, demonstrating that combining imaging with fluid analysis can help identify the real cause of respiratory problems and avoid unnecessary medication.

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