hyperlipidemia – mycolab.ai

Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials

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This comprehensive review examines how medicinal mushrooms contain natural compounds that can boost immune function, fight cancer cells, reduce inflammation, and protect nerve cells. Different mushroom species like reishi, shiitake, and maitake contain various active substances such as beta-glucans and triterpenes that work through multiple biological pathways. While laboratory and animal studies show promising results, more human clinical trials are needed to confirm effectiveness and establish safe dosing guidelines.

A Review on the Structure and Anti-Diabetic (Type 2) Functions of β-Glucans

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β-glucans are special sugar molecules found in foods like mushrooms, oats, and barley that can help control type 2 diabetes. These molecules work by two main methods: slowing down how quickly nutrients are absorbed in the digestive system, and blocking enzymes that break down carbohydrates into sugars. The shape and size of β-glucan molecules are very important—different structures have different effects on blood sugar control.

Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences

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This research shows that taking a specialized supplement containing natural plant compounds along with eating a Mediterranean diet can significantly help people with fatty liver disease. The supplement works by reducing harmful stress molecules in liver cells and calming down inflammation. After three months of treatment, patients showed improved liver health markers, better cholesterol levels, and improved blood sugar control. The study demonstrates that combining diet and targeted supplements is more effective than diet changes alone.

The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance

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This research review explores how mushroom compounds called polysaccharides may help manage diabetes by reducing harmful stress on cells caused by high glucose levels. Scientists found that 104 different mushroom polysaccharides have anti-diabetic properties and can protect insulin-producing cells in the pancreas. These natural compounds show promise as a complementary treatment to conventional diabetes medications, potentially with fewer side effects than synthetic drugs.

Fermented Rice Bran: A Promising Therapeutic Agent Against High-Fat Diet-Induced Metabolic Disorders

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Fermented rice bran, created by fermenting rice byproduct with beneficial bacteria, shows promise in helping manage weight and blood sugar levels in studies using rats on high-fat diets. The fermentation process increases the nutritional value of rice bran by boosting protein, fiber, and antioxidant content. Animals supplemented with fermented rice bran for 8 weeks showed improved cognitive function, better liver health, and improved lipid profiles compared to those on high-fat diets alone.

Evaluation of Lipid Changes During the Drying Process of Cordyceps sinensis by Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS)-Based Lipidomics Technique

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This study examines how different drying methods affect the lipid content of Cordyceps sinensis, a valuable medicinal mushroom. Researchers compared three drying techniques—freeze-drying, oven-drying, and air-drying—and found that freeze-drying best preserves the mushroom’s beneficial lipids, while oven-drying causes significant degradation. The findings provide practical guidance for mushroom producers on selecting optimal drying methods to maintain the medicinal quality and nutritional value of this prized fungus.

Use of Medicinal Mushrooms in Layer Ration

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This review discusses how medicinal mushrooms can be added to chicken feed to improve egg production and boost chicken health, offering a natural alternative to antibiotics. Several types of mushrooms like shiitake and oyster mushrooms have been shown to increase egg quality, strengthen immunity against diseases, and reduce cholesterol in eggs. These findings support the use of mushrooms as a sustainable solution for organic egg farming without compromising production or health.

Structural Elucidation, Modification, and Structure-Activity Relationship of Polysaccharides in Chinese Herbs: A Review

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This comprehensive review explains how the structure of plant polysaccharides from Chinese herbs determines their healing properties. The authors discuss various laboratory methods to identify polysaccharide structures and explain how chemical modifications can enhance their beneficial effects like boosting immunity and fighting tumors. The review provides guidance for researchers developing new polysaccharide-based medicines and shows that finding the right molecular size and chemical composition is key to maximizing therapeutic benefits.

Edible mushrooms as emerging biofactories for natural therapeutics and oral biopharmaceutical delivery

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Mushrooms are emerging as natural medicine factories that can be genetically engineered to produce medications taken by mouth. Beyond their traditional use as health foods, scientists are now using advanced genetic techniques to program mushrooms to manufacture therapeutic proteins and vaccines. These engineered mushrooms can naturally package and protect these medications as they pass through the stomach, releasing them safely in the intestines for absorption. This approach offers a sustainable, affordable, and cold-chain-independent alternative to conventional injected medications.

Nettle (Urtica cannabina L.) polysaccharides as a novel dietary supplement: enhancing systemic antioxidant status via modulation of the gut–liver axis

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This study found that nettle polysaccharides, especially at lower doses, act as a natural supplement that boosts the body’s antioxidant defenses. The supplement works by promoting beneficial bacteria in the gut, which produce helpful metabolites that signal to the liver to enhance protective antioxidant enzymes. These findings suggest nettle polysaccharides could be a promising natural ingredient for health-conscious food products aimed at maintaining metabolic wellness.

Disease: hyperlipidemia