Disease: hyperglycemia

Functional and Metabolomic Analyses of Chamomile Jelly Derived from Gelatin Capsule Waste with Inulin and Polydextrose as Prebiotic Sugar Substitutes

Researchers developed a healthy jelly product using leftover gelatin capsules from the pharmaceutical industry combined with chamomile tea and prebiotic fibers (inulin or polydextrose) as sugar substitutes. The best formulation containing 50% inulin substitution received the highest consumer preference while providing nutritional benefits, being cholesterol-free, and promoting beneficial bacteria growth. This innovative approach transforms industrial waste into a functional food that combines taste, health benefits, and sustainability.

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The Nearly Complete Genome of Grifola frondosa and Light-Induced Genes Screened Based on Transcriptomics Promote the Production of Triterpenoid Compounds

Researchers sequenced the complete genetic code of maitake mushroom (Grifola frondosa) and discovered how light exposure influences the production of beneficial compounds called triterpenoids. The high-quality genome assembly revealed 12,526 genes and showed that light triggers specific genes involved in making these medicinal compounds. This breakthrough provides a scientific foundation for growing maitake mushrooms with optimized levels of health-promoting substances.

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Enhancing Viability of Lactobacillus rhamnosus GG and Total Polyphenol Content in Fermented Black Goji Berry Beverage Through Calcium–Alginate Encapsulation with Hydrocolloids

Researchers developed a special technique to protect beneficial bacteria (Lactobacillus rhamnosus GG) in black goji berry juice so they survive the harsh conditions of the stomach and intestines. They used a coating made from alginate combined with ingredients like carrageenan or gelatin, which created a protective shield around the bacteria and helpful plant compounds. When this coated juice was taken with milk, the bacteria survived even better, making it a promising new way to deliver probiotics through plant-based beverages instead of traditional dairy products.

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Insights into the Mechanisms and Functional Effects of Insoluble Dietary Fiber Modification: A Review

Insoluble dietary fiber is important for digestive health but its rigid structure limits its usefulness in processed foods and medicine. Scientists can modify this fiber using various techniques like heating, pressure, enzymes, and chemicals to make it more effective. When combined properly, these modification strategies can dramatically improve dietary fiber’s ability to lower cholesterol, control blood sugar, and promote beneficial gut bacteria, making it valuable for functional foods and health applications.

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Biologically active secondary metabolites from white-rot fungi

White-rot fungi are special mushrooms that can break down wood and produce unique chemical compounds with amazing health benefits. These compounds have been found to fight cancer, kill harmful bacteria, reduce inflammation, and protect nerve cells. Scientists are excited about using these natural fungal compounds to create new medicines and treat various diseases in the future.

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Polysaccharides from fungi: A review on their extraction, purification, structural features, and biological activities

Mushrooms contain special compounds called polysaccharides that have powerful health benefits. Scientists have found these polysaccharides can help fight cancer, boost immunity, reduce inflammation, and manage diabetes. This review explains different ways to extract and purify these beneficial compounds from mushrooms and describes how they work in the body to provide these health benefits.

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Seagrass Enhalus acoroides extract mitigates obesity and diabetes via GLP-1, PPARγ, SREBP-1c modulation and gut microbiome restoration in diabetic zebrafish

Researchers tested a seagrass extract called Enhalus acoroides on diabetic zebrafish and found it effectively reduced body weight and blood sugar levels, performing as well or better than metformin, a common diabetes medication. The extract worked by activating genes that promote glucose metabolism and reducing genes that promote fat storage. Importantly, the extract also restored healthy gut bacteria balance, which appears to play a key role in its therapeutic effects. These findings suggest that seagrass could be developed into a natural supplement or functional food to help treat obesity and diabetes.

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From natural laboratory to drug discovery: Chemical structures, bioactivities, and biosynthesis of meroterpenoids from Ganoderma species

This review examines special compounds called meroterpenoids found in Ganoderma mushrooms (commonly known as Reishi). Scientists have identified over 350 of these compounds from 14 different Ganoderma species. These compounds show promise for treating various health conditions including cancer, kidney disease, diabetes, and inflammatory disorders. The researchers also propose how these compounds are made inside the mushroom, which could help scientists produce them more efficiently for medical use.

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Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

Researchers studied how adding olive mill waste to mushroom growing substrate affects the beneficial compounds in two edible mushrooms. They used advanced computer analysis of chemical data to find that this waste product increases healthy compounds like hericenones while reducing potentially harmful mycotoxins. This discovery could help make mushroom farming more sustainable and produce safer, healthier mushrooms for consumers.

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The value of microbial bioreactors to meet challenges in the circular bioeconomy

Scientists are using specially designed containers called bioreactors to grow helpful microorganisms and mushrooms that can solve environmental and health problems. These bioreactors can produce medicines like natural diabetes treatments from mushrooms, create eco-friendly plastics, clean up polluted water, and turn waste products into valuable materials. This approach is sustainable, safe, and scalable, supporting the United Nations’ goals for a healthier planet.

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