Disease: hepatocellular carcinoma

Current Approaches to Aflatoxin B1 Control in Food and Feed Safety: Detection, Inhibition, and Mitigation

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Aflatoxins are poisonous substances made by certain molds that contaminate about a quarter of the world’s food supply and are known carcinogens. This review examines the latest methods for detecting these toxins (from simple lab tests to advanced smartphone-powered devices) and ways to remove or prevent them, including using beneficial bacteria and special plasma treatment. The research shows that combining multiple approaches—detection technology with biological solutions—works best for keeping our food and animal feed safe from these dangerous contaminants.

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The Role of AFB1, OTA, TCNs, and Patulin in Forensic Sciences: Applications in Autopsy, Criminal Investigations, and Public Health Prevention

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This research examines how dangerous fungal poisons (mycotoxins) found in contaminated food can be detected in deceased individuals during autopsies. These toxins, produced by common molds, can cause serious health problems including liver cancer, kidney disease, and immune system damage. The study proposes procedures for forensic investigators to collect and analyze these toxins from body tissues and fluids to help solve cases involving poisoning or chronic toxin exposure.

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Mycotoxin contamination in Malawi: A systematic review of progress and trends in contamination, knowledge, attitude, and practices

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This review examines mycotoxin (toxic mold) contamination in Malawi and found that most people—farmers, traders, and health workers—don’t know about these dangerous substances or how to prevent them. Although groundnuts and maize are well-studied, other commonly eaten foods like dried fish and mushrooms have been largely ignored in research. Despite years of efforts to educate communities, awareness remains critically low at about 24.5%, and poverty often forces people to eat contaminated food because it’s cheaper.

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The Transformation and Protein Expression of the Edible Mushroom Stropharia rugosoannulata Protoplasts by Agrobacterium-tumefaciens-Mediated Transformation

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Researchers successfully developed a method to genetically modify the edible mushroom Stropharia rugosoannulata using Agrobacterium tumefaciens bacteria. This technique allows scientists to insert and express foreign genes in the mushroom, providing tools to study how specific genes control mushroom growth and the production of health-promoting compounds. The study demonstrates that both artificial and natural resistance markers can be used to identify successfully transformed mushrooms, offering a foundation for improving mushroom cultivation and breeding.

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Comparative Efficacy of Antrodia cinnamomea on Liver Function Biomarkers in Mice and Rats: A Network Meta-Analysis

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This study compared different extracts from a medicinal mushroom called Antrodia cinnamomea to see which ones work best for protecting liver health. Researchers analyzed data from multiple animal studies and found that extracts rich in compounds called triterpenoids were the most effective at improving liver function and reducing inflammation. The findings suggest that this mushroom could potentially become a natural treatment option for liver disease in the future.

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Mushroom Bioactive Molecules as Anticancerous Agents: An Overview

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Mushrooms contain natural compounds that show promise in fighting cancer by triggering cancer cell death and boosting immune function. Different mushroom species like oyster, shiitake, and button mushrooms contain substances such as beta-glucans and other polysaccharides that have demonstrated anticancer properties in laboratory and animal studies. While these mushroom compounds work through multiple mechanisms including preventing new blood vessel formation to tumors and stopping cancer cell division, more human clinical trials are needed to confirm their effectiveness as cancer treatments.

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