Disease: hepatocellular carcinoma

Tumor-associated macrophages in tumor progression and the role of traditional Chinese medicine in regulating TAMs to enhance antitumor effects

This review explains how tumor-associated macrophages (immune cells) can either fight or help cancer depending on their type. Traditional Chinese Medicine contains compounds that can reprogram these macrophages to fight cancer more effectively. By shifting macrophages from a cancer-supporting state to a cancer-fighting state, TCM treatments could enhance the body’s natural ability to combat tumors and reduce side effects of conventional cancer therapies.

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Isolation Techniques, Structural Characteristics, and Pharmacological Effects of Phellinus Polysaccharides: A Review

This review examines how scientists extract and study beneficial compounds called polysaccharides from a medicinal fungus called Phellinus. These polysaccharides show promise in fighting cancer, reducing inflammation, and boosting immune function. Different extraction methods affect the quality and effectiveness of these compounds, and researchers are working to optimize these techniques for better therapeutic applications.

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Lactic acid bacteria: beyond fermentation to bio-protection against fungal spoilage and mycotoxins in food systems

Mold and fungal toxins spoil food and threaten human health, costing billions globally. While chemical preservatives work, many consumers want natural alternatives. Lactic acid bacteria (the same organisms used in yogurt production) produce natural antimicrobial compounds that can prevent mold growth and neutralize harmful toxins, offering a safer, more natural way to keep food fresh longer.

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Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products

Mushrooms have been used for health for thousands of years and contain special compounds that help boost the immune system and fight cancer. Scientists have identified several key active ingredients in mushrooms like polysaccharides and proteins that can activate immune cells and reduce tumors. Some mushroom products like lentinan from shiitake mushrooms have already been approved as cancer treatments in Japan. While most evidence comes from lab studies, ongoing research suggests mushroom-based medicines could become important therapeutic options.

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Research progress of edible mushroom polysaccharide-metal trace element complexes

This research reviews how edible mushroom polysaccharides can be combined with essential metals like iron, selenium, and zinc to create health-boosting supplements. These complexes improve how our bodies absorb and use these important minerals, offering benefits like better immune function, antioxidant protection, and potential cancer-fighting properties. Scientists are studying different ways to make these complexes and testing their effectiveness for treating various health conditions.

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The Gut Mycobiome for Precision Medicine

This comprehensive review explores how fungi in our gut play important roles in our health and disease. While fungi make up only a tiny fraction of our gut microbiota, they have outsized effects on conditions like diabetes, inflammatory bowel disease, and even certain cancers. The review discusses how scientists study these fungi and how understanding individual fungal profiles could lead to personalized medical treatments tailored to each person’s unique microbial makeup.

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Current Uses of Mushrooms in Cancer Treatment and Their Anticancer Mechanisms

This comprehensive review examines how medicinal mushrooms can help treat cancer. Certain mushroom species and their compounds, particularly polysaccharides, can boost the immune system to fight cancer cells, reduce chemotherapy side effects, and overcome drug resistance. Multiple mushrooms are currently in clinical trials showing promise in improving cancer patient outcomes when used alongside conventional treatments.

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Can Ganoderma Triterpenoids Exert Immunogenic Cell Death in Human Cancer Cells? A Systematic Review and Protein Network Analysis

This review examines whether compounds from medicinal mushrooms called Ganoderma can help the body’s immune system fight cancer more effectively. Researchers analyzed 69 scientific studies and found that Ganoderma compounds cause cancer cells to die and trigger immune-activating signals. While these results are promising, more experiments are needed to prove whether these mushroom compounds actually activate the specific immune pathways required for long-term cancer control.

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Glycosylation and sugar variations in tyrosol yield promising prebiotic-like effects

This study tested whether chemically modified versions of tyrosol, a natural compound found in olives and red wine, could boost beneficial gut bacteria better than the original form. Researchers gave mice three different versions: plain tyrosol, natural salidroside (tyrosol with glucose attached), and a lab-created version with galactose attached instead. The galactose version worked best, promoting the most beneficial bacteria like Bifidobacteria and reducing harmful bacteria, potentially offering health benefits similar to prebiotic supplements.

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Increased Dissemination of Aflatoxin- and Zearalenone-Producing Aspergillus spp. and Fusarium spp. during Wet Season via Houseflies on Dairy Farms in Aguascalientes, Mexico

This study found that during rainy seasons on Mexican dairy farms, houseflies carry more mold spores that produce harmful toxins called aflatoxins and zearalenone. These toxins contaminate cattle feed and milk, posing health risks to both animals and humans. The research shows that controlling houseflies during wet seasons is crucial to reduce toxic mold contamination of dairy products and animal feed.

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