Disease: hepatic fibrosis

Development and preliminary mechanistic analysis of compound effervescent hepatoprotective granules

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Researchers developed a new health product combining three medicinal plants to protect the liver from injury. The mixture contains effective compounds that reduce liver inflammation, fight harmful oxidative stress, and protect liver cells from damage. Studies in rats showed the product improved liver function and reduced markers of liver damage, suggesting it could be useful for preventing and treating liver injuries caused by drugs, alcohol, or toxins.

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The Active Components of Traditional Chinese Medicines Regulate the Multi-Target Signaling Pathways of Metabolic Dysfunction-Associated Fatty Liver Disease

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This comprehensive review examines how traditional Chinese medicine ingredients can treat fatty liver disease through multiple biological pathways simultaneously. Unlike conventional drugs that target a single pathway, TCM compounds address the complex, interconnected causes of the disease including fat accumulation, inflammation, and tissue damage. The research identifies dozens of effective herbal compounds and proposes a new framework for designing TCM treatments tailored to individual patient needs.

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Optimization of triterpenoids biosynthesis in Athelia termitophila as a source of natural products

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Researchers optimized growing conditions for a parasitic termite fungus called Athelia termitophila to produce more triterpenoids, which are medicinal compounds with health benefits. By systematically testing different nutrients and fermentation parameters, they increased triterpenoid production by 1.9 times and fungal biomass by 1.66 times. This breakthrough makes it more practical and cost-effective to produce these natural compounds for use in pharmaceuticals and functional foods.

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Optimization of triterpenoids biosynthesis in Athelia termitophila as a source of natural products

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Researchers optimized growing conditions for a fungus found in termite nests to dramatically increase production of triterpenoids, naturally-occurring compounds with potent health benefits. Using statistical methods to test different nutrients and conditions, they nearly doubled triterpenoid production and mycelial biomass. These findings could make triterpenoid-based medicines and supplements more affordable and widely available by improving natural production methods.

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Characterizing flavor determinants and α-glucosidase inhibitory components in ancient tea plants and ‘Qiancha 1’ white teas

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Researchers compared white teas made from ancient tea plants (over 100 years old) with modern cultivated tea varieties. The ancient teas had stronger floral aromas and more bitter taste due to higher levels of beneficial compounds. These compounds, particularly trans-β-ionone and β-damascenone, may help regulate blood sugar levels, making ancient tea plants valuable for both flavor and potential health benefits.

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