Disease: hematologic malignancy

Fungal Pneumonia and Severe Neutropenia: Risk Factors for Increased 90 Day Mortality

This study examined 39 cancer patients with severe fungal lung infections treated at a major cancer center. Patients who received antifungal treatment within 7 days and started with a specific drug called liposomal amphotericin B had better survival rates at 90 days. The research suggests that quick diagnosis and prompt treatment initiation are critical for improving survival in immunocompromised patients with fungal pneumonia.

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Invasive Cutaneous Mucormycosis in a Patient With Chronic Lymphocytic Leukemia on Obinutuzumab, Idelalisib, and Bruton Tyrosine Kinase Degrader: A Case Report

A 74-year-old man with leukemia developed a serious fungal infection (mucormycosis) on his ankle while taking cancer-fighting drugs. The infection was diagnosed through tissue biopsy examination rather than standard culture tests. Treatment required both powerful antifungal medications and surgical removal of the infected leg below the knee. The patient recovered successfully after this aggressive treatment approach.

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