Disease: hematologic malignancies

Multidisciplinary Integrative Medicine Approach for Cancer Patients: A Multicenter Retrospective Study

This study shows that when cancer patients use complementary treatments like mushroom supplements, vitamins, and probiotics alongside their cancer medications under doctor supervision, they experience fewer side effects and better quality of life. Almost 93% of patients had no side effects from these supplements, and many reported less fatigue and better overall wellness. The key finding is that patients should work with their medical team rather than self-prescribing these treatments to avoid dangerous interactions.

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Brazilian task force for the management of mucormycosis

Mucormycosis is a serious fungal infection that has become more common in Brazil, especially during COVID-19. This medical emergency requires rapid diagnosis through imaging and tissue sampling, combined with aggressive treatment including antifungal medications and surgery to remove infected tissue. The Brazilian government has made these powerful antifungal drugs more available to improve patient survival and reduce the severe complications of this dangerous infection.

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Efficacy assessments of SF001, a next-generation polyene antifungal, in a neutropenic mouse model of invasive fusariosis

This study tested a new antifungal drug called SF001 against a serious infection called fusariosis in mice. SF001 performed as well as the current standard treatment (amphotericin B) but with better safety profiles. The drug successfully reduced fungal infections in organs and improved survival rates in infected mice without showing signs of toxicity at higher doses.

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Cryptococcus: Emerging host risk factors for infection

This scientific review examines why some people without HIV are getting serious Cryptococcus infections and becoming very sick. Researchers found that people with liver problems, kidney disease, diabetes, cancer, and autoimmune diseases face much higher risk. The review also identifies new drugs and therapies that can surprisingly increase infection risk, highlighting the importance of understanding individual patient factors when treating these dangerous fungal infections.

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Cellular Composition of Bronchoalveolar Lavage Fluid in Patients with Hematologic Malignancies and Invasive Pulmonary Aspergillosis: Significant Associations with Peripheral Blood Cell Counts

Researchers studied lung fluid samples from cancer patients with a serious fungal lung infection called invasive pulmonary aspergillosis. They found that blood cell counts in the lungs correlated with blood cell counts overall, but surprisingly, the cell composition in lung fluid did not predict patient survival. The study highlights that doctors need better ways to assess the lung’s immune response to this serious fungal infection beyond just counting cells.

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