Disease: Green mold disease in Agaricus bisporus

Providing a toolbox for genomic engineering of Trichoderma aggressivum

Scientists have created a set of tools to genetically engineer Trichoderma aggressivum, a fungus that causes green mold disease in cultivated mushrooms but can also be used beneficially. The study provides step-by-step methods for transforming this fungus using both traditional plasmid methods and modern CRISPR gene-editing technology. These tools will help researchers understand how the fungus works and potentially harness its beneficial properties for agriculture.

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Providing a toolbox for genomic engineering of Trichoderma aggressivum

Scientists have developed a set of techniques to genetically modify the fungus Trichoderma aggressivum, which is usually known for ruining mushroom crops. This genetic toolkit allows researchers to edit genes in this fungus to study how it produces various compounds and why it affects mushrooms. By using modern gene-editing technology called CRISPR, researchers can now create specific mutations and study the fungus’s useful properties, such as its potential to protect crops or promote plant growth.

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