Disease: Glioblastoma

Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

This review examines how traditional Chinese medicine ingredients can boost the body’s natural ability to fight cancer when combined with tiny nanoparticles that deliver drugs more effectively. The nanoparticles help TCM compounds work better by improving how they dissolve, how long they stay in the body, and where they target. By activating immune cells like natural killer cells and dendritic cells while reducing immune-suppressing cells, this combination approach offers a promising new strategy for cancer treatment with fewer side effects.

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The Anticancer Potential of Edible Mushrooms: A Review of Selected Species from Roztocze, Poland

This review examines edible mushrooms found in Poland’s Roztocze region for their potential to fight cancer. These mushrooms contain natural compounds like polysaccharides and proteins that can kill cancer cells in laboratory studies through various mechanisms, including triggering cell death and boosting immune function. While promising, these findings from laboratory and animal studies need further development before becoming clinical treatments.

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Chaga mushroom triterpenoids as adjuncts to minimally invasive cancer therapies: A review

Chaga mushroom, a fungus that grows on birch trees, contains special compounds called triterpenoids that can kill cancer cells in laboratory tests. Some of these compounds, particularly inotodiol and betulinic acid, show anti-cancer activity similar to or better than conventional chemotherapy drugs. While promising, researchers need to improve how these compounds are absorbed in the body and test them more thoroughly in animals and humans before they can be used clinically.

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Fungal Drug Discovery for Chronic Disease: History, New Discoveries and New Approaches

This article examines how fungi have provided humanity with some of the most important medicines ever created, including penicillin, drugs that prevent organ rejection, and cholesterol-lowering statins. Many of these fungal compounds work as medicines because they target processes that are similar in both fungi and humans, helping them survive competition with other fungi while coincidentally treating human diseases. New researchers are now using modern genetic tools to discover additional fungal medicines, with several promising candidates currently being tested in clinical trials for cancer, depression, and other chronic diseases.

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Isolation Techniques, Structural Characteristics, and Pharmacological Effects of Phellinus Polysaccharides: A Review

This review examines how scientists extract and study beneficial compounds called polysaccharides from a medicinal fungus called Phellinus. These polysaccharides show promise in fighting cancer, reducing inflammation, and boosting immune function. Different extraction methods affect the quality and effectiveness of these compounds, and researchers are working to optimize these techniques for better therapeutic applications.

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Current Uses of Mushrooms in Cancer Treatment and Their Anticancer Mechanisms

This comprehensive review examines how medicinal mushrooms can help treat cancer. Certain mushroom species and their compounds, particularly polysaccharides, can boost the immune system to fight cancer cells, reduce chemotherapy side effects, and overcome drug resistance. Multiple mushrooms are currently in clinical trials showing promise in improving cancer patient outcomes when used alongside conventional treatments.

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Can Ganoderma Triterpenoids Exert Immunogenic Cell Death in Human Cancer Cells? A Systematic Review and Protein Network Analysis

This review examines whether compounds from medicinal mushrooms called Ganoderma can help the body’s immune system fight cancer more effectively. Researchers analyzed 69 scientific studies and found that Ganoderma compounds cause cancer cells to die and trigger immune-activating signals. While these results are promising, more experiments are needed to prove whether these mushroom compounds actually activate the specific immune pathways required for long-term cancer control.

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How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?

This comprehensive review explores how traditional healing practices from around the world use plants and mushrooms to treat cancer. The authors examine thousands of plant species and their active compounds that show promise in fighting various types of cancer through multiple mechanisms like stopping cancer cell growth and triggering cell death. The review emphasizes that proper scientific validation, standardization, and safety testing can help integrate these traditional remedies into modern cancer treatment alongside conventional chemotherapy.

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Phytochemicals as promising agents in Axl-targeted cancer treatment

This review examines natural plant compounds that can block Axl, a protein that helps cancer cells survive and spread. Scientists found that compounds from common foods like apples, grapes, green tea, ginger, and chamomile can reduce Axl levels and kill cancer cells. These natural compounds work through different mechanisms and show promise for treating various cancers, including those resistant to standard chemotherapy drugs.

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