gastrointestinal perforation

Disseminated mucormycosis leading to a fatal gastrointestinal perforation in a pediatric case of EBV-associated Hemophagocytic lymphohistiocytosis

mycolabadmin

A 12-month-old girl with a severe immune system disorder (HLH) triggered by Epstein-Barr virus developed a life-threatening fungal infection (mucormycosis) that spread throughout her digestive system. Despite aggressive treatment with multiple antifungal medications and emergency surgery, the infection caused her intestines to perforate, leading to her death. The case highlights the difficulty in recognizing fungal infections early in immunocompromised children and the need for heightened clinical awareness.

Disseminated mucormycosis leading to a fatal gastrointestinal perforation in a pediatric case of EBV-associated Hemophagocytic lymphohistiocytosis

mycolabadmin

A 12-month-old girl with a serious immune system disorder called HLH developed a rare and dangerous fungal infection called mucormycosis. Despite receiving the best available treatments, the fungal infection spread throughout her digestive system and caused a perforation (hole) in her intestines. The doctors found it difficult to diagnose the fungal infection early because the warning signs were subtle, and the infection progressed very rapidly. Unfortunately, the girl passed away despite emergency surgery and high-dose antifungal medications.

Disseminated mucormycosis leading to a fatal gastrointestinal perforation in a pediatric case of EBV-associated Hemophagocytic lymphohistiocytosis

mycolabadmin

A 12-month-old girl developed a serious immune system disorder called hemophagocytic lymphohistiocytosis triggered by Epstein-Barr virus infection. Despite aggressive treatment, she developed a life-threatening fungal infection caused by mucormycosis that spread throughout her digestive system. The case illustrates how fungal infections can rapidly progress and become fatal in children with severely weakened immune systems, emphasizing the need for doctors to recognize early warning signs like tissue darkening on the skin.

Disease: gastrointestinal perforation

Disseminated mucormycosis leading to a fatal gastrointestinal perforation in a pediatric case of EBV-associated Hemophagocytic lymphohistiocytosis

Disseminated mucormycosis leading to a fatal gastrointestinal perforation in a pediatric case of EBV-associated Hemophagocytic lymphohistiocytosis

Disseminated mucormycosis leading to a fatal gastrointestinal perforation in a pediatric case of EBV-associated Hemophagocytic lymphohistiocytosis