Disease: gastrointestinal infections

A Review of the Role of Paraprobiotics in the Formulation of High-Protein Ice Cream as an Advanced Functional Food

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Paraprobiotics are inactivated bacterial cells that offer the same health benefits as live probiotics but are much more stable and don’t require refrigeration. When added to high-protein ice cream, paraprobiotics help boost immune function and gut health while improving the product’s texture and shelf-life. This makes paraprobiotic-enriched ice cream an ideal functional dessert for athletes, people with dietary restrictions, and anyone seeking healthier frozen food options.

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Antibiofilm activity and bioactive phenolic compounds of ethanol extract from the Hericium erinaceus basidiome

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Researchers tested a lion’s mane mushroom extract for its ability to stop harmful bacteria from forming protective biofilms that make infections harder to treat. The extract showed strong activity against Proteus mirabilis bacteria, reducing biofilm formation by over 78%. The antibiofilm power comes mainly from two phenolic compounds: protocatechuic acid and p-coumaric acid. These findings suggest lion’s mane mushroom could be developed into natural supplements or food preservatives to prevent bacterial contamination.

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Pathogenic mucorales: Deciphering their cell wall polysaccharidome and immunostimulatory potential

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Mucormycosis is a dangerous fungal infection that kills many immunocompromised patients. Researchers analyzed the outer layer (cell wall) of three common disease-causing fungi and discovered that their surfaces contain sugar-like molecules that trigger strong inflammatory responses from the immune system. This excessive inflammation may actually contribute to the disease’s severity, suggesting that controlling inflammation alongside antifungal treatment might improve patient outcomes.

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Gut fungal profiles reveal phylosymbiosis and codiversification across humans and nonhuman primates

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Researchers studied fungal communities in the guts of humans and various primates to understand how these fungi evolved alongside their hosts. They discovered that more closely related primate species have more similar fungal communities, and that some fungi show signs of evolving together with primates over millions of years. These findings suggest that gut fungi are long-term partners with their hosts rather than temporary travelers from diet alone.

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Fungal pathogens and symbionts: Living off the fat of the land

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Certain fungi that live exclusively in or on hosts have evolved a clever survival strategy: they stopped making their own fatty acids and instead steal them from their hosts. This includes fungi that cause pneumonia in immunocompromised patients, yeasts on skin, and beneficial fungi that help plants absorb nutrients from soil. By examining how these fungi scavenge fatty acids from their hosts, scientists hope to develop better treatments and diagnostic tools for fungal infections.

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A novel, cheap and easy preparing selective medium for isolation of Pythium species

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Researchers have created an inexpensive and easy-to-use growth medium called FANS that effectively isolates disease-causing Pythium fungi from soil and water samples. Unlike expensive laboratory media containing toxic chemicals, FANS uses affordable pharmaceutical antibiotics costing about $11.55 per liter. This new medium successfully prevents contamination from other fungi and bacteria while promoting Pythium growth, making it especially valuable for scientists in developing countries studying plant diseases and pythiosis infections.

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